2. Stem Cell/Wnt
  3. Wnt
  4. 4,4'-Di-O-methylellagic acid

4,4'-Di-O-methylellagic acid  (Synonyms: 4,4'-DiOMEA; Nasutin C)

目录号: HY-N7171
产品使用指南 技术支持

4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) 可以从澳大利亚白蚁中分离出来。 Nasutin C 在紫外光下发出蓝色荧光。4,4'-Di-O-methylellagic acid 通过 wnt 信号通路抑制结肠癌细胞增殖。

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4,4'-Di-O-methylellagic acid Chemical Structure

4,4'-Di-O-methylellagic acid Chemical Structure

CAS No. : 3374-77-4

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4,4'-Di-O-methylellagic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4,4'-Di-O-methylellagic acid (4,4'-DiOMEA; Nasutin C) can be isolated from the Australian termites. 4,4'-Di-O-methylellagic acid is blue-fluorescent under ultra-violet light[1]. 4,4'-Di-O-methylellagic acid inhibits colon cancer cell proliferation via the wnt signal pathway[2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Erythrocyte IC50
1.1 mM
Compound: 9
Anticomplement activity in sheep erythrocytes assessed as concentration required for 50% hemolytic inhibition by classic pathway pretreated for 10 mins with guinea pig serum followed by erythrocyte addition measured after 30 mins by spectrophotometeric me
Anticomplement activity in sheep erythrocytes assessed as concentration required for 50% hemolytic inhibition by classic pathway pretreated for 10 mins with guinea pig serum followed by erythrocyte addition measured after 30 mins by spectrophotometeric me
[PMID: 29631958]
Erythrocyte IC50
1.31 mM
Compound: 9
Anticomplement activity in rabbit erythrocytes assessed as concentration required for 50% hemolytic inhibition by alternative pathway pretreated for 10 mins with normal human serum followed by erythrocyte addition measured after 30 mins by spectrophotomet
Anticomplement activity in rabbit erythrocytes assessed as concentration required for 50% hemolytic inhibition by alternative pathway pretreated for 10 mins with normal human serum followed by erythrocyte addition measured after 30 mins by spectrophotomet
[PMID: 29631958]
分子量

330.25

Formula

C16H10O8
CAS 号
结构分类
初始来源

Nasutitermes exitiosus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4,4'-Di-O-methylellagic acid 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4,4'-Di-O-methylellagic acid3374-77-44,4'-DiOMEA Nasutin CWntBlue-FluorescentInhibitorinhibitorinhibit

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