1. 多肽产品
  2. 多肽及其衍生物
  3. 激素肽与神经肽
  4. Neuromedin U-25 (human)

Neuromedin U-25 human 是 Neuromedin U 在人体内的活性形式。Neuromedin U-25 human 抑制葡萄糖刺激的胰岛素分泌,从而导致早发性肥胖。Neuromedin U-25 在人血管床中充当血管收缩剂。

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Custom Peptide Synthesis

Neuromedin U-25 (human) Chemical Structure

Neuromedin U-25 (human) Chemical Structure

CAS No. : 312306-89-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds[1][2].

体外研究
(In Vitro)

Neuromedin U-25 human (4 pM-2 nM) 与人左心室和冠状动脉中的受体结合,KD 分别为 0.26 和 0.11 nM[1]
Neuromedin U-25 human (0.1 nM-0.1 μM) 内皮非依赖性地收缩冠状动脉、乳动脉和隐静脉,收缩效力 pD2 分别为 8.6,8.0 和 8.2[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

3080.37

Formula

C141H203N41O38

CAS 号
Sequence

Phe-Arg-Val-Asp-Glu-Glu-Phe-Gln-Ser-Pro-Phe-Ala-Ser-Gln-Ser-Arg-Gly-Tyr-Phe-Leu-Phe-Arg-Pro-Arg-Asn-NH2

Sequence Shortening

FRVDEEFQSPFASQSRGYFLFRPRN-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Neuromedin U-25 (human)
目录号:
HY-P2378
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