Ramucirumab (Synonyms: 雷莫芦单抗)

目录号: HY-P9920 纯度: 99.40%: FAQs
Data Sheet SDS COA

摩尔计算器

Ramucirumab 是人 VEGFR-2 拮抗剂，具有抗实体瘤作用。Ramucirumab 是一种人源单克隆抗体，可与 VEGFR-2 结合，阻止 VEGFR 配体 VEGF-A，VEGF-C 和 VEGF-D 结合。Ramucirumab 也是一种血管生成抑制剂。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Ramucirumab Chemical Structure

CAS No. : 947687-13-0

1. 客户无需承担相应的运输费用。

2. 同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

可免费申领三个不同产品的试用装。

3. 试用装只面向终端客户。

规格	价格	是否有货
1 mg	￥1900	In-stock
5 mg	￥5500	In-stock
25 mg		询价
50 mg		询价

or 大包装询价

* Please select Quantity before adding items.

Customer Review

MCE 顾客使用本产品发表的 2 篇科研文献

Ramucirumab 相关产品

•同靶点产品:

•同靶点蛋白产品:

查看 VEGFR 亚型特异性产品:

查看所有亚型

VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

生物活性
实验参考方法
纯度 & 产品资料
参考文献

生物活性

Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab is also an angiogenesis inhibitor^[1]^[2].

IC₅₀ & Target^[1]^[2]

VEGFR-2

体外研究
(In Vitro)

Ramucirumab (10 μg/mL) 阻碍 VEGF 和肿瘤驱动的索形成^[3]。
Ramucirumab 不与小鼠 VEGFR2 发生交叉反应^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

143609.63

Formula

C₆₃₇₄H₉₈₆₄N₁₆₉₂O₁₉₉₆S₄₆

CAS 号

947687-13-0

性状

液体

颜色

Colorless to light yellow

中文名称

雷莫芦单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: 99.40%

选择批次：

Data Sheet (519 KB) SDS (251 KB)

COA (151 KB)

抗体抑制剂使用指南 (1152 KB)

参考文献

[1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53. [Content Brief]

[2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5. [Content Brief]

[3]. Lowery CD, et al. Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy. Oncotarget. 2019 Sep 17;10(53):5523-5533. [Content Brief]

Cell Assay	MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53. [Content Brief] [2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5. [Content Brief] [3]. Lowery CD, et al. Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy. Oncotarget. 2019 Sep 17;10(53):5523-5533. [Content Brief]

Cell Assay

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Fala L. Cyramza (Ramucirumab) Approved for the Treatment of Advanced Gastric Cancer and Metastatic Non-Small-Cell Lung Cancer. Am Health Drug Benefits. 2015 Mar;8(Spec Feature):49-53. [Content Brief]

[2]. Oholendt AL, et al. Ramucirumab: A New Therapy for Advanced Gastric Cancer. J Adv Pract Oncol. 2015 Jan-Feb;6(1):71-5. [Content Brief]

[3]. Lowery CD, et al. Anti-VEGFR2 therapy delays growth of preclinical pediatric tumor models and enhances anti-tumor activity of chemotherapy. Oncotarget. 2019 Sep 17;10(53):5523-5533. [Content Brief]

Ramucirumab 相关分类

摩尔计算器
稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量		浓度		体积		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)	×	体积 _(start)	=	浓度 _(final)	×	体积 _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ramucirumab947687-13-0雷莫芦单抗VEGFRVascular endothelial growth factor receptorangiogenesis inhibitorNSCLCnon–small-cell lung cancergastric cancerInhibitorinhibitorinhibit

您最近查看的产品:

产品名称：

* 需求量：

* 客户姓名：

* Email：

* 电话：

* 公司或机构名称：

留言给我们：

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)	站点地图隐私声明
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.	沪ICP备15051369号-4

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)

站点地图隐私声明

Ramucirumab (Synonyms: 雷莫芦单抗)

Customer Review

MCE 顾客使用本产品发表的 2 篇科研文献

Ramucirumab 相关产品

•同靶点产品:

•同靶点蛋白产品:

查看 VEGFR 亚型特异性产品:

生物活性

实验参考方法

纯度 & 产品资料

参考文献

Ramucirumab 相关分类

摩尔计算器

稀释计算器

The molarity calculator equation

The dilution calculator equation

Keywords:

您最近查看的产品:

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

产品名称：			* Lot #：
* 客户姓名：			* Email：
电话：			* 部门：
* 公司或机构名称：
留言给我们：

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

Ramucirumab (Synonyms: 雷莫芦单抗)

Customer Review

Ramucirumab 相关抗体

MCE 顾客使用本产品发表的 2 篇科研文献

Ramucirumab 相关产品

•同靶点产品:

•同靶点蛋白产品:

查看 VEGFR 亚型特异性产品:

生物活性

实验参考方法

纯度 & 产品资料

参考文献

Ramucirumab 相关抗体:

Ramucirumab 相关分类

摩尔计算器

稀释计算器

The molarity calculator equation

The dilution calculator equation

Keywords:

您最近查看的产品:

Request for HNMR Report

Request for HNMR Report

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z