Cathepsin C/DPPI 蛋白, Mouse (His-Myc)

The cathepsin C/DPPI protein is a thiol protease that acts as a dipeptidyl peptidase with multiple substrate specificities, excluding proline at the P1 position and arginine at the P2 position. It has both exopeptidase and endopeptidase functions and can activate serine proteases such as elastase, cathepsin G, and granzymes A and B. Cathepsin C/DPPI Protein, Mouse (His-Myc) is the recombinant mouse-derived Cathepsin C/DPPI protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of Cathepsin C/DPPI Protein, Mouse (His-Myc) is 110 a.a., with molecular weight of 20.1 kDa.

组织蛋白酶 C/DPPI 蛋白作为硫醇蛋白酶发挥作用，表现出二肽基肽酶活性，可有效对抗多种包含极性和疏水性氨基酸的二肽底物。值得注意的是，底物中的 P1 位置不能容纳脯氨酸，P2 位置不能容纳精氨酸。这种硫醇蛋白酶显示出作为外肽酶和内肽酶的多功能性。其功能范围延伸至丝氨酸蛋白酶的激活，包括弹性蛋白酶、组织蛋白酶 G 以及颗粒酶 A 和 B。组织蛋白酶 C/DPPI 的广泛底物特异性和多功能作用突出了其在复杂的蛋白水解过程网络中的重要性，暗示其参与不同的细胞功能和调节途径。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Mouse

E. coli

N-10*His;C-Myc

P97821 (D25-W134)

13032

DTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHETMTGWVHDVLGRNW

20.1 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.