1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. OTULIN 蛋白, Human (His, GST)

OTULIN 蛋白, Human (His, GST)

目录号: HY-P703376
产品使用指南 技术支持

OTULIN 蛋白, Human (His, GST) 是重组的 OTULIN 蛋白,由 E. coli 表达,带有 His, GST 标签。OTULIN 蛋白, Human (His, GST)

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
10 μg ¥2400 1 - 2 周
50 μg ¥6800 1 - 2 周
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

OTULIN Protein, Human (His, GST) is the recombinant human-derived OTULIN, expressed by E. coli , with His, GST labeled tag. ,

研究背景

OTULIN 是一种特异性去除线性('Met-1' 连接)多聚泛素链的去泛素化酶,通过调控 LUBAC 复合物的活性,在血管生成、先天免疫反应以及 Wnt 和 NF-kappa-B 信号通路中发挥重要作用。它在血管生成、颅面和神经元发育过程中通过调控经典 Wnt 信号通路发挥作用,同时作为 LUBAC 复合物的负调控因子,通过去除其自身泛素化修饰维持其活性。OTULIN 在炎症和免疫稳态中起关键作用,限制自发性炎症和细胞因子分泌,并在 NOD2 刺激时限制 LUBAC 复合物上的线性泛素化形成以调控先天免疫反应。by similar:OTULIN 的功能主要集中于 LUBAC 复合物的稳态调控。

种属

Human

表达系统

E. coli

标签

His;GST

蛋白编号

Q96BN8 (M1-L352)

基因 ID

90268

蛋白长度

Full Length

中文名
OTULIN 蛋白
同用名
FAM105B
预测分子量
68 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE

性状

溶液.

组分

Supplied as a 0.22 μm filtered solution of 50 mM HEPES (pH 7.5), 200mM NaCl, 20% glycerol, 1mM DTT.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

Please use rapid thawing with running water to thaw the protein.

保存条件 & 期限

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料

OTULIN Protein, Human (His, GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
OTULIN Protein, Human (His, GST)
目录号:
HY-P703376
需求量: