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Serum amyloid A-3 protein/Saa3 蛋白, Mouse (P.pastoris, His)

目录号: HY-P71809
COA 产品使用指南

血清淀粉样蛋白 A-3 蛋白/SAA3 是一种重要的急性期反应物,在应对急性生理挑战中发挥关键作用。作为高密度脂蛋白 (HDL) 复合物中重要的载脂蛋白,SAA3 有助于脂质代谢的调节,显示出其在维持体内平衡方面的多方面作用。Serum amyloid A-3 protein/SAA3 蛋白, Mouse (P.pastoris, His) 是重组的 血清淀粉样蛋白 A-3 蛋白/SAA3 蛋白,由 P. pastoris 表达,带有 N-6*His 标签。

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描述

Serum amyloid A-3 protein/SAA3 is an important acute-phase reactant that plays a key role in responding to acute physiological challenges.As an important apolipoprotein in high-density lipoprotein (HDL) complexes, SAA3 contributes to the regulation of lipid metabolism, demonstrating its multifaceted role in maintaining homeostasis.Serum amyloid A-3 protein/SAA3 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Serum amyloid A-3 protein/SAA3 protein, expressed by P.pastoris , with N-6*His labeled tag.

研究背景

血清淀粉样蛋白 A-3 蛋白(也称为 Saa3)是一种重要的急性期反应物,在人体对急性生理挑战的反应中发挥着关键作用。作为高密度脂蛋白 (HDL) 复合物中的重要载脂蛋白,Saa3 有助于脂质代谢的调节,凸显其在维持体内平衡方面的多方面参与。值得注意的是,体外研究揭示了其对大肠杆菌、乳房链球菌和铜绿假单胞菌的抗菌活性,表明其在针对细菌病原体的先天免疫防御中具有潜在作用。这种双重功能强调了 Saa3 在急性期反应和抗菌防御机制中的多样化和重要贡献。

种属

Mouse

表达系统

P. pastoris

标签

N-6*His

蛋白编号

P04918 (R20-Y122)

基因 ID

20210  [NCBI]

蛋白结构
N-term
6*His
SAA3 (R20-Y122)
Accession # P04918
C-term
同用名
Saa3; Serum amyloid A-3 protein
氨基酸序列

RWVQFMKEAGQGSRDMWRAYSDMKKANWKNSDKYFHARGNYDAARRGPGGAWAAKVISDAREAVQKFTGHGAEDSRADQFANEWGRSGKDPNHFRPAGLPKRY

分子量

Approximately 15 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized after extensive dialysis against solution in 20 mM Tris-HC1, 0.5 M NaCl, 6% Trehalose, pH 8.0 or PBS, 6% Trehalose, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

Serum amyloid A-3 protein/Saa3 Protein, Mouse (P.pastoris, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Serum amyloid A-3 protein/Saa3 Protein, Mouse (P.pastoris, His)
目录号:
HY-P71809
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