2. Metabolic Enzyme/Protease
  3. Aminopeptidase Neprilysin
  4. SDUY816

SDUY816 是一种具有口服活性的双重 APN/NEP 抑制剂，对 APN 和 NEP 的 IC50 分别为 0.68 和 6.9 μM。SDUY816 具有镇痛作用，且具有良好的安全性和药代动力学特性，在大鼠 (口服，10 mg/kg) 中具有 27% 的生物口服利用度和 4.02 小时的半衰期。SDUY816 可用于神经性疼痛疾病领域的研究。

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SDUY816 Chemical Structure

SDUY816 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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SDUY816 相关抗体

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CD13 Leukotriene A4 hydrolase

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SDUY816 is an oral active dual APN/NEP inhibitor, with IC50 values of 0.68 μM for APN and 6.9 μM for NEP. SDUY816 exhibits analgesic effects and demonstrates good safety and pharmacokinetic profiles, with an oral bioavailability of 27% and a half-life of 4.02 hours in rats (oral administration, 10 mg/kg). SDUY816 has potential applications in the research of neuropathic pain disorders[1].

分子量

449.24

Formula

C18H16IN3O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SDUY816 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SDUY816SDUY 816SDUY-816AminopeptidaseNeprilysinNeutral endopeptidaseNEPCluster of differentiation 10CD10Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-170961
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