1. Others
  2. Others
  3. Stepronin

Stepronin  (Synonyms: Prostenoglycine; TTPG; Tiase)

目录号: HY-A0234 纯度: 99.93%
COA 产品使用指南

Stepronin (Prostenoglycine) 是一种口服有效的祛痰剂 (吸入给药优于口服给药)。Stepronin 在体外通过减少上皮细胞的 Cl- 分泌和粘膜下腺体的粘液糖蛋白分泌来抑制气道分泌。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Stepronin Chemical Structure

Stepronin Chemical Structure

CAS No. : 72324-18-6

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
Free Sample (0.1 - 0.2 mg)   Apply now  
5 mg ¥900
In-stock
10 mg ¥1400
In-stock
50 mg ¥4200
In-stock
100 mg ¥6500
In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Stepronin (Prostenoglycine) is an orally active expectorant (inhalation administration is preferable to oral administration). Stepronin inhibits airway secretion in vitro by reducing Cl- secretion from epithelial cells and mucus glycoprotein secretion from submucosal glands[1].

体外研究
(In Vitro)

Stepronin (0.1-100 µM; 20 min) induces significant reductions in ISOP(Isoproterenol)-evoked SCC (short circuit current) value in a dose-dependent manner in canine tracheal epithelium[1].
Stepronin (10-100 µM; 20 min) significantly inhibits the basal secretion and ISOP-evoked PD (potential difference) value in a dose-dependent manner in canine tracheal epithelium[1].
Stepronin (100 µM; 20 min) significantly inhibits ISOP-induced [3H]-glycoconjugate secretion in submucosal glands[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: Canine tracheal epithelium (from adult and 10 to 25 kg-weight mongrel dogs of both sexes)
Concentration: 0.1-100 µM; 10-100 µM
Incubation Time: 20 min (pre-treat)
Result: Significantly inhibited ISOP-induced SCC and PD values, as well as basal secretion.

Cell Viability Assay[1]

Cell Line: Submucosal glands (from adult and 10 to 25 kg-weight mongrel dogs of both sexes)
Concentration: 100 µM
Incubation Time: 20 min (pre-treat)
Result: Significantly inhibited ISOP- induced [3H]-glycoconjugate secretion.
分子量

273.33

Formula

C10H11NO4S2

CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

DMSO 中的溶解度 : ≥ 250 mg/mL (914.65 mM; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.6586 mL 18.2929 mL 36.5858 mL
5 mM 0.7317 mL 3.6586 mL 7.3172 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Stepronin 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6586 mL 18.2929 mL 36.5858 mL 91.4645 mL
5 mM 0.7317 mL 3.6586 mL 7.3172 mL 18.2929 mL
10 mM 0.3659 mL 1.8293 mL 3.6586 mL 9.1465 mL
15 mM 0.2439 mL 1.2195 mL 2.4391 mL 6.0976 mL
20 mM 0.1829 mL 0.9146 mL 1.8293 mL 4.5732 mL
25 mM 0.1463 mL 0.7317 mL 1.4634 mL 3.6586 mL
30 mM 0.1220 mL 0.6098 mL 1.2195 mL 3.0488 mL
40 mM 0.0915 mL 0.4573 mL 0.9146 mL 2.2866 mL
50 mM 0.0732 mL 0.3659 mL 0.7317 mL 1.8293 mL
60 mM 0.0610 mL 0.3049 mL 0.6098 mL 1.5244 mL
80 mM 0.0457 mL 0.2287 mL 0.4573 mL 1.1433 mL
100 mM 0.0366 mL 0.1829 mL 0.3659 mL 0.9146 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Stepronin
目录号:
HY-A0234
需求量: