1. Apoptosis
  2. Apoptosis
  3. Triethylenetetramine dihydrochloride

Triethylenetetramine dihydrochloride  (Synonyms: Trientine dihydrochloride; TETA dihydrochloride)

目录号: HY-B1807A
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Triethylenetetramine (TETA) dihydrochloride 是一种具有口服活性、强效和选择性的铜螯合剂。Triethylenetetramine dihydrochloride 促进二价铜离子从体内排出,减少肠道对铜的吸收,减少铜的积累。Triethylenetetramine dihydrochloride 通过端粒酶抑制、抗血管生成和促进癌细胞凋亡 (apoptosis) 等机制显示出潜在的抗癌活性。Triethylenetetramine dihydrochloride 有望用于威尔森氏病、癌症和糖尿病并发症的研究。

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Triethylenetetramine dihydrochloride Chemical Structure

Triethylenetetramine dihydrochloride Chemical Structure

CAS No. : 38260-01-4

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  • 生物活性

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  • 参考文献

生物活性

Triethylenetetramine (TETA) dihydrochloride is an orally active, potent and selective copper chelating agent. Triethylenetetramine dihydrochloride promotes the excretion of divalent copper ions from the body and reduces intestinal copper absorption, reducing copper accumulation. Triethylenetetramine dihydrochloride exhibits potential anti-cancer activity through mechanisms such as telomerase inhibition, anti-angiogenesis, and promotion of cancer cell apoptosis. Triethylenetetramine dihydrochloride is promising for research of Wilson's disease, cancer, and diabetic complications[1][2].

分子量

219.16

同用名

Trientine dihydrochloride; TETA dihydrochloride

Formula

C6H20Cl2N4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Triethylenetetramine dihydrochloride 相关分类

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Triethylenetetramine dihydrochloride
目录号:
HY-B1807A
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