1. Apoptosis
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  3. Triethylenetetramine tetrahydrochloride

Triethylenetetramine tetrahydrochloride  (Synonyms: Trientine tetrahydrochloride; TETA tetrahydrochloride)

目录号: HY-W013273
产品使用指南 技术支持

Triethylenetetramine (Trientine) tetrahydrochloride 是一种具有口服活性、强效和选择性的铜螯合剂。Triethylenetetramine tetrahydrochloride 促进二价铜离子从体内排出,减少肠道对铜的吸收,减少铜的积累。Triethylenetetramine tetrahydrochloride 通过端粒酶抑制、抗血管生成和促进癌细胞凋亡 (apoptosis) 等机制显示出潜在的抗癌活性。Triethylenetetramine tetrahydrochloride 有望用于威尔森氏病、癌症和糖尿病并发症的研究。

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Triethylenetetramine tetrahydrochloride Chemical Structure

Triethylenetetramine tetrahydrochloride Chemical Structure

CAS No. : 4961-40-4

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  • 生物活性

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  • 参考文献

生物活性

Triethylenetetramine (Trientine) tetrahydrochloride is an orally active, potent and selective copper chelating agent. Triethylenetetramine tetrahydrochloride promotes the excretion of divalent copper ions from the body and reduces intestinal copper absorption, reducing copper accumulation. Triethylenetetramine tetrahydrochloride exhibits potential anti-cancer activity through mechanisms such as telomerase inhibition, anti-angiogenesis, and promotion of cancer cell apoptosis. Triethylenetetramine tetrahydrochloride is promising for research of Wilson's disease, cancer, and diabetic complications[1][2].

分子量

292.08

Formula

C6H22Cl4N4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Triethylenetetramine tetrahydrochloride 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Triethylenetetramine tetrahydrochloride
目录号:
HY-W013273
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