1. GPCR/G Protein
    Neuronal Signaling
  2. mAChR
  3. Atropine methyl bromide

Atropine methyl bromide (Synonyms: Methylatropine bromide)

目录号: HY-112076
产品使用指南

Atropine methyl bromide, 是毒蕈碱型受体 (mAChR) 的拮抗剂,是阿托品的季铵盐,是眼科检查时用于瞳孔扩张的药物。由于其高度极性,被用于缓解婴儿幽门痉挛。它比阿托品更不易进入中枢神经系统。

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Atropine methyl bromide Chemical Structure

Atropine methyl bromide Chemical Structure

CAS No. : 2870-71-5

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥5720 In-stock
10 mg ¥5200 In-stock
50 mg ¥15000 In-stock
100 mg ¥21000 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist, is a quaternary ammonium salt of atropine and a mydriatic for dilation of the pupil during ophthalmic examination. It is introduced for relieving pyloric spasm in infants for its highly polar nature. It penetrates less readily into the central nervous system than atropine[1][2].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 150 mg/mL (390.31 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6021 mL 13.0103 mL 26.0207 mL
5 mM 0.5204 mL 2.6021 mL 5.2041 mL
10 mM 0.2602 mL 1.3010 mL 2.6021 mL
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液。
In Vivo:
  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (6.51 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (6.51 mM); Clear solution

  • 3.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (6.51 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
Molecular Weight

384.31

Formula

C₁₈H₂₆BrNO₃

CAS No.

2870-71-5

SMILES

C[N+]1([C@H]2C[C@H](OC(C(C3=CC=CC=C3)CO)=O)C[C@@H]1CC2)C.[Br-]

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Atropine methyl bromide
目录号:
HY-112076
需求量:

Atropine methyl bromide

Cat. No.: HY-112076