Serotonin (Synonyms: 5-Hydroxytryptamine; 5-HT)

目录号: HY-B1473A 纯度: 99.86%: Data Sheet SDS COA 产品使用指南
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Serotonin 是 CNS 中的单胺神经递质和内源性 5-HT 受体激动剂。Serotonin 也是儿茶酚 O-甲基转移酶 (COMT) 的抑制剂，其 K_i 值为 44 μM。

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Serotonin Chemical Structure

CAS No. : 50-67-9

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规格	价格	是否有货
1 mg	￥600	In-stock
5 mg	￥1200	In-stock
10 mg	￥1800	In-stock
25 mg	￥3200	In-stock
50 mg	￥4800	In-stock
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Other Forms of Serotonin:

MCE 顾客使用本产品发表的 15 篇科研文献

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5-HT Receptor 5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor

生物活性
实验参考方法
纯度 & 产品资料
参考文献

生物活性

Serotonin is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin is also a catechol O-methyltransferase (COMT) inhibitor with a K_i of 44 μM.

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

细胞效力
(Cellular Effect)

Cell Line	Type	Value	Description	References
B16	IC₅₀	> 30 μM Compound: 17	Antimelanogenic activity in mouse B16 cells assessed as inhibition of intracellular melanin accumulation after 2 days Antimelanogenic activity in mouse B16 cells assessed as inhibition of intracellular melanin accumulation after 2 days	[PMID: 19524439]
C6	EC₅₀	12 nM Compound: 5-HT	Agonist activity at human 5HT4 isoform E receptor expressed in rat C6 cells assessed as cAMP accumulation by radio-immunoassay relative to 5HT Agonist activity at human 5HT4 isoform E receptor expressed in rat C6 cells assessed as cAMP accumulation by radio-immunoassay relative to 5HT	[PMID: 19334715]
CHO	EC₅₀	0.7 nM Compound: 5-HT	Agonist activity assessed by stimulation of [35S]GTP-gamma-S binding to human 5HT1A receptor expressed in CHO cells Agonist activity assessed by stimulation of [35S]GTP-gamma-S binding to human 5HT1A receptor expressed in CHO cells	[PMID: 16458504]
CHO	EC₅₀	1 nM Compound: 5-HT	Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulation Agonistic activity at human 5HT1A in CHO cells by the inhibition of forskolin-stimulated cAMP accumulation	[PMID: 16392798]
CHO	IC₅₀	1.2 x 10^-1 μM Compound: Serotonin	Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in CHO cells measured after 120 mins by scintillation counting method Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in CHO cells measured after 120 mins by scintillation counting method	[PMID: 27876250]
CHO	EC₅₀	1.5 nM Compound: 5-HT	Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate reader Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate reader	[PMID: 15081042]
CHO	EC₅₀	1.63 nM Compound: 5-HT	Agonist activity at 5HT2C receptor expressed in CHO cells by fluorescence based calcium mobilization assay Agonist activity at 5HT2C receptor expressed in CHO cells by fluorescence based calcium mobilization assay	[PMID: 22381048]
CHO	EC₅₀	1.7 nM Compound: 5-HT	Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate reader Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometric imaging plate reader	[PMID: 15081042]
CHO	EC₅₀	11 nM Compound: 5-HT	Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometric imaging plate reader Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometric imaging plate reader	[PMID: 15081042]
CHO	EC₅₀	150 nM Compound: 5-HT	Agonist activity at 5HT1A receptor expressed in CHO cells by [35S]GTPgammaS binding assay Agonist activity at 5HT1A receptor expressed in CHO cells by [35S]GTPgammaS binding assay	[PMID: 19559623]
CHO	IC₅₀	2.5 x 10^-10 M Compound: Serotonin	Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells measured after 120 mins by scintillation counting method Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cells measured after 120 mins by scintillation counting method	[PMID: 27876250]
CHO	EC₅₀	25 nM Compound: 5-HT	Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assay	[PMID: 19646865]
CHO	EC₅₀	4.67 nM Compound: 1	The intrinsic activity was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryptamine 1B receptor in CHO cell line; Full Agonist The intrinsic activity was evaluated for its ability to inhibit forskolin-stimulated c-AMP formation mediated by cloned 5-hydroxytryptamine 1B receptor in CHO cell line; Full Agonist	[PMID: 9871775]
CHO-K1	EC₅₀	0.07 μM Compound: Serotonin	Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemiluminescence analysis Agonist activity at human recombinant 5-HT7 receptor expressed in CHOK1 Hunter cell incubated for 30 to 60 mins by hit-hunter cAMP assay based chemiluminescence analysis	[PMID: 32631561]
CHO-K1	EC₅₀	15 nM Compound: Serotonin	Agonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as increase in cAMP levels by HTRF assay Agonist activity at human recombinant 5HT7 receptor expressed in CHOK1 cells assessed as increase in cAMP levels by HTRF assay	[PMID: 19326916]
CHO-K1	EC₅₀	15.33 nM Compound: 5-HT	Agonist activity at 5-HT1A receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 by Fluo-4 dye based FLIPR assay Agonist activity at 5-HT1A receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 by Fluo-4 dye based FLIPR assay	[PMID: 27487565]
CHO-K1	EC₅₀	16 nM Compound: 5-HT	Agonist activity at 5HT2A receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay Agonist activity at 5HT2A receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay	[PMID: 23675993]
CHO-K1	EC₅₀	18 nM Compound: Serotonin	Agonist activity at human recombinant 5HT1A receptor (unknown origin) stably expressed in CHO-K1 incubated for 30 mins by [35S]GTPgammaS binding assay Agonist activity at human recombinant 5HT1A receptor (unknown origin) stably expressed in CHO-K1 incubated for 30 mins by [35S]GTPgammaS binding assay	[PMID: 31627993]
CHO-K1	EC₅₀	39 nM Compound: 5-HT	Agonist activity at 5HT1A receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay Agonist activity at 5HT1A receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assay	[PMID: 23675993]
CHO-K1	EC₅₀	4.82 nM Compound: 5-HT	Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cells Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cells	[PMID: 8960551]
CHO-K1	EC₅₀	45.3 nM Compound: Serotonin	Partial agonist activity at recombinant human 5-HT1A expressed in CHO-K1 cells by pathhunter beta-arrestin assay Partial agonist activity at recombinant human 5-HT1A expressed in CHO-K1 cells by pathhunter beta-arrestin assay	[PMID: 32631554]
CHO-K1	EC₅₀	47 nM Compound: 5-HT	Agonist activity at 5-HT2A receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 by Fluo-4 dye based FLIPR assay Agonist activity at 5-HT2A receptor (unknown origin) expressed in CHOK1 cells co-expressing G-alpha 15 by Fluo-4 dye based FLIPR assay	[PMID: 27487565]
Flp-In-293	EC₅₀	0.19 nM Compound: Serotonin	Agonist activity at recombinant human unedited 5HT2C receptor isoform INI expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fluo-4 dye based FLIPR assay Agonist activity at recombinant human unedited 5HT2C receptor isoform INI expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fluo-4 dye based FLIPR assay	[PMID: 31445232]
Flp-In-293	EC₅₀	0.27 nM Compound: Serotonin	Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fluo-4 dye based FLIPR assay Agonist activity at recombinant human 5HT2A receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fluo-4 dye based FLIPR assay	[PMID: 31445232]
Flp-In-293	EC₅₀	0.86 nM Compound: Serotonin	Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fluo-4 dye based FLIPR assay Agonist activity at recombinant human 5HT2B receptor expressed in Flp-In-293 cells assessed as increase in calcium influx measured for 300 secs by Fluo-4 dye based FLIPR assay	[PMID: 31445232]
HEK293	EC₅₀	0.00087 μM Compound: 5-HT, serotonin	Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by fluorescence assay Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by fluorescence assay	[PMID: 23301527]
HEK293	EC₅₀	0.0026 μM Compound: 5-HT, serotonin	Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by fluorescence assay Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as induction of intracellular calcium release measured for 90 secs by fluorescence assay	[PMID: 23301527]
HEK293	EC₅₀	0.017 μM Compound: 5-HT, serotonin	Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assay Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assay	[PMID: 25073094]
HEK293	EC₅₀	0.044 μM Compound: 5-HT, serotonin	Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins at RT by TR-FRET assay Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins at RT by TR-FRET assay	[PMID: 23301527]
HEK293	EC₅₀	0.09 nM Compound: 5-HT	Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay	[PMID: 22778800]
HEK293	EC₅₀	0.09 nM Compound: 1	Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay	[PMID: 19284718]
HEK293	EC₅₀	0.1 μM Compound: serotonin	Activity at SER4 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay Activity at SER4 receptor expressed in HEK293 cells assessed as increase in calcium by calcium imaging assay	[PMID: 18033297]
HEK293	EC₅₀	0.15 μM Compound: 5-HT, serotonin	Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins at RT by TR-FRET assay Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as accumulation of IP1 incubated for 1 hr at 37 degC followed by 15 mins at RT by TR-FRET assay	[PMID: 23301527]
HEK293	EC₅₀	0.17 nM Compound: 5-HT	Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay Agonist activity at human 5-HT2C-INI receptor isoform expressed in Flp-IN HEK293 cells assessed as induction of Gq-mediated calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay	[PMID: 28657744]
HEK293	EC₅₀	0.21 nM Compound: 5-HT	Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay	[PMID: 25633969]
HEK293	EC₅₀	0.4 nM Compound: 5-HT	Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as increase in calcium mobilization by FLIPR assay Agonist activity at human 5-HT2C receptor expressed in HEK293 cells assessed as increase in calcium mobilization by FLIPR assay	[PMID: 23602445]
HEK293	EC₅₀	0.41 nM Compound: 5-HT	Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at 1 sec interval for 60 secs by Fluo-4 calcium dye based FLIPR assay	[PMID: 32282200]
HEK293	EC₅₀	0.5 nM Compound: 1	Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay	[PMID: 19284718]
HEK293	EC₅₀	0.5 μM Compound: 5-HT	Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assay Antagonist activity at human 5HT3A receptor expressed in HEK293 cells by FMP assay	[PMID: 17722904]
HEK293	EC₅₀	0.86 nM Compound: 5-HT	Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay Agonist activity at human 5HT2B receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay	[PMID: 22778800]
HEK293	EC₅₀	0.92 nM Compound: 5-HT	Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay	[PMID: 25633969]
HEK293	EC₅₀	1.1 nM Compound: 5-HT	Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as increase in calcium mobilization by FLIPR assay Agonist activity at human 5-HT2B receptor expressed in HEK293 cells assessed as increase in calcium mobilization by FLIPR assay	[PMID: 23602445]
HEK293	EC₅₀	1.46 nM Compound: 5-HT	Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay Agonist activity at human 5-HT2B receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay	[PMID: 28657744]
HEK293	EC₅₀	1.5 nM Compound: 5-HT	Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as increase in calcium mobilization by FLIPR assay Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as increase in calcium mobilization by FLIPR assay	[PMID: 23602445]
HEK293	IC₅₀	1.8 x 10^-1 μM Compound: Serotonin	Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in HEK293 cells measured after 120 mins by scintillation counting method Displacement of [3H]LSD from human recombinant 5HT5A receptor expressed in HEK293 cells measured after 120 mins by scintillation counting method	[PMID: 27876250]
HEK293	EC₅₀	1.88 nM Compound: 5-HT	Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Agonist activity at human 5-HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay	[PMID: 25633969]
HEK293	EC₅₀	2.35 nM Compound: 5-HT	Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay Agonist activity at human 5-HT2A receptor expressed in Flp-IN HEK293 cells assessed as induction of calcium flux measured every second for 5 mins by Fluo-4 dye based FLIPR assay	[PMID: 28657744]
HEK293	IC₅₀	260 nM Compound: Serotonin	Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation counting Displacement of [3H]LSD from human recombinant 5-HT5a receptor in HEK293 cells after 120 mins by scintillation counting	[PMID: 27997171]
HEK293	EC₅₀	3.75 nM Compound: 5-HT	Agonist activity at 5-HT1A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS binding by scintillation proximity assay Agonist activity at 5-HT1A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of [35S]GTPgammaS binding by scintillation proximity assay	[PMID: 23332346]
HEK293	EC₅₀	5.8 nM Compound: 1	Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay	[PMID: 19284718]
HEK293	EC₅₀	5.8 nM Compound: 5-HT	Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye based fluorescence assay Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye based fluorescence assay	[PMID: 27475109]
HEK293	EC₅₀	7.6 nM Compound: 5-HT	Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay Agonist activity at human 5HT2A receptor expressed in HEK293 cells assessed as calcium flux measured every sec for 3 mins by FLIPR assay	[PMID: 22778800]
U2OS	IC₅₀	1.25 nM Compound: Serotonin	Antagonist activity at recombinant human 5-HT2C expressed in human U2OS cells by pathhunter beta-arrestin assay Antagonist activity at recombinant human 5-HT2C expressed in human U2OS cells by pathhunter beta-arrestin assay	[PMID: 32631554]
U2OS	IC₅₀	27.9 nM Compound: Serotonin	Antagonist activity at recombinant human 5-HT2A expressed in human U2OS cells by pathhunter beta-arrestin assay Antagonist activity at recombinant human 5-HT2A expressed in human U2OS cells by pathhunter beta-arrestin assay	[PMID: 32631554]

体外研究
(In Vitro)

Serotonin 是中枢神经系统中的单胺类神经递质，也是内源性 5-HT 受体激动剂。Serotonin 还通过非竞争性结合儿茶酚底物结合位点来抑制儿茶酚 O-甲基转移酶 (COMT)，儿茶酚 O-甲基转移酶是一种有助于调节疼痛感知的酶，其结合亲和力与儿茶酚本身的结合亲和力相当 (K_i=44 μM)。结果表明，添加 100 μM Serotonin 会降低 COMT 的反应速度^[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

与接受盐水治疗的对照组相比，Serotonin 会产生强烈的超敏反应 (p<0.001)^[1]。
在诱发 DSS 结肠炎后，接受 Serotonin 的 IL-13^-/- 小鼠的结肠 5-HT 含量显著增加，而接受载体的 IL-13^-/- 小鼠的结肠 5-HT 含量则较少^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

分子量

176.22

Formula

C₁₀H₁₂N₂O

CAS 号

50-67-9

性状

固体

颜色

White to off-white

中文名称

5-羟色胺；血清胺

结构分类

初始来源

内源性代谢物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: 99.86%

选择批次：

Data Sheet (554 KB) SDS (419 KB)

COA (285 KB) RP-HPLC (258 KB) 元素分析报告 (209 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25. [Content Brief]

[2]. Shajib MS, et al. Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation. PLoS One. 2013 Aug 28;8(8):e72774. [Content Brief]

Cell Assay ^[2]	For macrophage culture, peritoneal cavity cells are collected from WT and IL-13^-/- mice with or without dextran sodium sulfate (DSS) treatment and cultured. Cells are plated at a concentration of 3.0×10⁶ cells per millilitre, and treated with either lipopolysaccharides (LPS); (100 ng/mL) or Serotonin (10^-10 M) for 24 hours. The culture supernatant are collected and stored in -80°C until determination of cytokine levels using protein array system^[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Administration ^[2]	Dextran sodium sulfate (DSS) colitis is induced by orally administering 5% DSS in drinking water for 5 days. In a separate experiment, IL-13^-/- mice are injected subcutaneously with 100 mg/kg of Serotonin (5-HTP) twice daily for 8 days beginning 3 days prior to induction of DSS colitis; whereas, the control IL-13^-/- mice receive saline as vehicle. Animals are anaesthetized prior to euthanization via cervical dislocation at the conclusion of each experiment or if they reach a predetermined end point (ie, loss of ≥20% body weight and/or significant deterioration of body condition)^[2]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Tsao D, et al. Serotonin-induced hypersensitivity via inhibition of catechol O-methyltransferase activity. Mol Pain. 2012 Apr 13;8:25. [Content Brief] [2]. Shajib MS, et al. Interleukin 13 and serotonin: linking the immune and endocrine systems in murine models of intestinal inflammation. PLoS One. 2013 Aug 28;8(8):e72774. [Content Brief]

Serotonin 相关分类

Neurological Disease

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Keywords:

Serotonin50-67-95-Hydroxytryptamine 5-HT5-羟色胺血清胺5-HT ReceptorCOMTEndogenous MetaboliteSerotonin Receptor5-hydroxytryptamine ReceptorCatechol-O-methyltransferaseInhibitorinhibitorinhibit

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Serotonin (Synonyms: 5-Hydroxytryptamine; 5-HT)

Other Forms of Serotonin:

MCE 顾客使用本产品发表的 15 篇科研文献

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纯度 & 产品资料

参考文献

Serotonin 相关分类

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The dilution calculator equation

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Serotonin (Synonyms: 5-Hydroxytryptamine; 5-HT)

Other Forms of Serotonin:

Serotonin 相关抗体

MCE 顾客使用本产品发表的 15 篇科研文献

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生物活性

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