1. Metabolic Enzyme/Protease
  2. Dopamine β-hydroxylase

Dopamine β-hydroxylase

Dopamine β-hydroxylase (Dopamine beta-hydroxylase, Dopamine beta-monooxygenase) is an enzyme that in humans is encoded by the DBH gene. Dopamine β-monooxygenase catalyzes the chemical reaction with 3 substrates of 3,4-dihydroxyphenethylamine, ascorbate, and O2, whereas its 3 products are noradrenaline, dehydroascorbate, and H2O. Dopamine β-hydroxylase belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. Dopamine β-hydroxylase participates in tyrosine metabolism. Dopamine β-hydroxylase has 3 cofactors: copper, PQQ, and Fumarate. Dopamine β-hydroxylase is in the catecholamine biosynthetic pathway. Dopamine β-hydroxylase has been shown to be associated with decision making and addictive behaviors such as alcohol and smoking, attention deficit hyperactivity disorder, and also with neurological diseases such as Schizophrenia and Alzheimer's.

Dopamine β-hydroxylase 相关产品 (2):

Cat. No. Product Name Effect Purity
  • HY-13289A
    Nepicastat hydrochloride Inhibitor 99.74%
    Nepicastat(SYN117; RS-25560-197)盐酸盐是多巴胺_beta_-羟化酶高效抑制剂,对牛源和人源巴胺_beta_-羟化酶的IC50值分别为8.5和9.0nM。
  • HY-13289
    Nepicastat Inhibitor
    Nepicastat (SYN117; RS-25560-197)是多巴胺β羟化酶抑制剂,对牛和人的多巴胺β羟化酶的IC50分别为8.5nM和9.0nM。
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