2. Apoptosis Protein Tyrosine Kinase/RTK
  3. Apoptosis VEGFR
  4. Apoptotic agent-4

Apoptotic agent-4 (Compound 9) 是一种细胞凋亡 (Apoptosis) 诱导剂。Apoptotic agent-4 抑制 VEGFR-2，IC50 为 0.5717 μM。Apoptotic agent-4 抑制癌细胞增殖并将细胞阻滞在 G2/M 和 Pre-G1 期。

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Apoptotic agent-4 Chemical Structure

Apoptotic agent-4 Chemical Structure

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Apoptotic agent-4 相关抗体

Top Publications Citing Use of Products

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Apoptotic agent-4 (Compound 9) is a apoptosis inducer. Apoptotic agent-4 inhibits VEGFR-2 with an IC50 of 0.5717 μM. Apoptotic agent-4 inhibits cancer cell proliferation and arrests the cell at both the G2/M and Pre-G1 phases[1].

IC50 & Target[1]

VEGFR2

0.5717 μM (IC50)

体外研究
(In Vitro)

Apoptotic agent-4 对 HCT-116、HepG-2、MCF-7 细胞具有抗增殖作用，IC50s 分别为 8.05、5.15、9.77 μM。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptotic agent-4 相关抗体:
分子量

460.61

Formula

C22H28N4O3S2
Unlabeled CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Apoptotic agent-4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Apoptotic agent-4Apoptotic agent4Apoptotic agent 4ApoptosisVEGFRVascular endothelial growth factor receptorHCT-116HepG-2MCF-7anticancerInhibitorinhibitorinhibit

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