2. Gene
  3. NMS - neuromedin S Gene

NMS - neuromedin S Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：神经调节素 S

种属: Homo sapiens

基因 ID: 129521 | 基因类型: protein coding

关于 NMS

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:100,470,482-100,483,280 (from NCBI)

This gene has 1 transcript (splice variant) and 86 orthologues. Low expression observed in reference dataset.

功能概要

该基因编码神经肽神经调节蛋白家族的成员。编码的前原蛋白经过蛋白水解处理，产生具有生物活性的神经肽，在调节昼夜节律、引起厌食作用、抗利尿作用、心血管功能以及刺激催产素和加压素释放方面发挥作用。[RefSeq 提供，2016 年 5 月]

This gene encodes a member of the neuromedin family of neuropeptides. The encoded preproprotein is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. [provided by RefSeq, May 2016]

NMS 基因产物(1)

mRNA Protein Name
NM_001011717.1 NP_001011717.1 neuromedin-S preproprotein
蛋白主名 其他名称

neuromedin-S

neuromedin S precursor-related peptide/neuromedin S preproprotein

关联疾病

疾病名称 别名
Type 1 Diabetes Mellitus 2

Diabetes Mellitus, Noninsulin-Dependent, 1

Diabetes Mellitus, Insulin-Dependent, 2

IDDM2

Insulin-Dependent Diabetes Mellitus 2

NIDDM1

Diabetes Mellitus, Noninsulin-Dependent 1

T1D2

Type 2 Diabetes Mellitus 1

T2D1

Noninsulin-Dependent Diabetes Mellitus 1

Diabetes Mellitus, Non-Insulin-Dependent, 1

Type 2 Diabetes Mellitus 1, Susceptibility To

Diabetes Mellitus, Insulin-Dependent, Type 2

Diabetes Mellitus, Non-Insulin-Dependent
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Approval
生物活性分子 (4)
目录号 产品名 作用方式
纯度 是否罕见病
HY-12678 Entrectinib 99.79% 是
HY-B0267 Oxybutynin 99.86% 是
HY-B0267A Oxybutynin chloride 98.49% 是
HY-B0267AR Oxybutynin chloride (Standard) / 否
Clinical Phase
生物活性分子 (7)
目录号 产品名 作用方式
纯度 Phase
HY-15828 Onvansertib 99.83% Phase 2
HY-18099A S1RA hydrochloride Antagonist 99.94% Phase 2
HY-18099 S1RA Antagonist 99.43% Phase 2
HY-12108 S 1360 Inhibitor / Phase 2
HY-117288 S55746 Inhibitor 99.91% Phase 1
HY-15114 S 17092 Inhibitor 99.78% Phase 1
HY-117288A S55746 hydrochloride Inhibitor 99.66% Phase 1
Pre-clinical Phase
生物活性分子 (42)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15713 NMS-873 Inhibitor 99.92% 否
HY-122136 S26131 Antagonist 99.63% 否
HY-12382 NMS-P715 Inhibitor 99.30% 否
HY-17547 NMS-E973 Inhibitor 99.61% 否
HY-112257 S-23 Modulator 99.93% 否
HY-146695 S100P-IN-1 Inhibitor 99.74% 否
HY-15714 NMS-859 Inhibitor 98.05% 否
HY-152189 S19-1035 99.77% 否
HY-18954 NMS-P118 Inhibitor 99.54% 否
HY-114962 S-22153 Antagonist 99.88% 否
HY-12678S1 Entrectinib-d8 99.82% 否
HY-122203 PCS1055 dihydrochloride 98.88% 否
HY-128599 NMS-P515 Inhibitor 98.18% 否
HY-156672 S6K2-IN-1 Inhibitor 98.75% 否
HY-103267 S32826 disodium Inhibitor 98.85% 否
HY-122203A PCS1055 98.02% 否
HY-145153 S-777469 Agonist 98.83% 否
HY-149804 S1R agonist 2 Agonist ≥98.0% 否
HY-119366 S18-000003 Inhibitor 99.31% 否
HY-12678S Entrectinib-d4 Inhibitor / 否
HY-149803 S1R agonist 1 Agonist ≥98.0% 否
HY-149803A S1R agonist 1 hydrochloride Agonist 99.83% 否
HY-103117 S 32212 hydrochloride Inhibitor / 否
HY-103267A S32826 Inhibitor / 否
HY-108263A (S)-3-Hydroxy Midostaurin Inhibitor / 否
HY-115566 S1PL-IN-1 / 否
HY-125743 S-1 Methanandamide Agonist 98.00% 否
HY-143690S Oxybutynin-d10 hydrochloride / 否
HY-146380 S1427 Inhibitor / 否
HY-149804A S1R agonist 2 hydrochloride Agonist ≥98.0% 否
HY-156249 NMS-P528 / 否
HY-156299 NMS-P945 / 否
HY-161331 S16–1029 Inhibitor / 否
HY-162427 NMS-0963 Inhibitor / 否
HY-171138 Mal-VC-PAB-DMEA-PNU-159682 Inhibitor / 否
HY-176533 S1PR5-IN-1 Inhibitor / 否
HY-RS09388 NMS Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-129679 NMS-P953 Inhibitor / 否
HY-149210 S1PR1 ligand 1 / 否
HY-164514 NMS-P626 Inhibitor / 否
HY-RS18899 Nms Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25390 Nms Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus NMS MGD MGI:3583618
Bos taurus NMS VGNC VGNC:32136
Rattus norvegicus NMS RGD RGD:1359122
Canis familiaris NMS VGNC VGNC:108209
Macaca mulatta NMS VGNC VGNC:75289
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