RPL41 - ribosomal protein L41 Gene

中文名称：核糖体蛋白 L41

种属: Homo sapiens

同用名: L41

关于 RPL41

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 60S 亚基的一个组成部分。该蛋白质与酵母核糖体蛋白 YL41 具有序列相似性，属于核糖体蛋白 L41E 家族。它位于细胞质中。该蛋白可与蛋白激酶 CKII 的 β 亚基相互作用，并可刺激 CKII 对 DNA 拓扑异构酶 II-α 的磷酸化。已经鉴定出两种可变剪接变体，它们都编码相同的蛋白质。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with the yeast ribosomal protein YL41, belongs to the L41E family of ribosomal proteins. It is located in the cytoplasm. The protein can interact with the beta subunit of protein kinase CKII and can stimulate the phosphorylation of DNA Topoisomerase II-alpha by CKII. Two alternative splice variants have been identified, both encoding the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]