2. Others Immunology/Inflammation Epigenetics Autophagy Cell Cycle/DNA Damage NF-κB Apoptosis PI3K/Akt/mTOR
  3. PARP Autophagy Keap1-Nrf2 NF-κB NOD-like Receptor (NLR) Reference Standards Sirtuin Pyroptosis Apoptosis AMPK
  4. Sweroside (Standard)

Sweroside (Standard) 

目录号: HY-N0806R 纯度: ≥98%
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Swerosid (Standard) 是 Sweroside (HY-N0806) 的分析标准品。本产品用于研究及分析应用。Sweroside 是一种环烯醚萜苷，可靶向 Keap1/Nrf2 轴、NLRP3 炎症小体、SIRT1、NF-κB、AMPK/mTOR 通路及 caspase 家族等多个靶点。Sweroside 通过竞争性结合 Keap1 促进 Nrf2 核转位。Sweroside 还通过激活 Nrf2 抑制氧化应激、抑制 NLRP3 介导的焦亡 (pyroptosis)、激活 SIRT1 抑制 NF-κB 炎症通路，并经 AMPK/mTOR 通路促进自噬 (autophagy)、诱导 caspase 依赖的凋亡 (apoptosis)。Sweroside 具有抗氧化、抗炎、抗凋亡、调节脂质代谢等活性，可用于心肌缺血再灌注损伤、白血病、急性肺损伤、非酒精性脂肪肝等领域的研究。

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Sweroside (Standard) Chemical Structure

Sweroside (Standard) Chemical Structure

CAS No. : 14215-86-2

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规格 价格 是否有货 数量
5 mg ￥900
3 - 5 周
10 mg ￥1500
3 - 5 周
25 mg ￥3000
3 - 5 周
50 mg ￥4800
3 - 5 周
100 mg ￥7680
3 - 5 周
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

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生物活性

Sweroside (Standard) is the analytical standard of Sweroside (HY-N0806). This product is intended for research and analytical applications. Sweroside is an iridoid glycoside that targets multiple targets, including the Keap1/Nrf2 axis, NLRP3 inflammasome, SIRT1, NF-κB, AMPK/mTOR pathway, and caspase family. Sweroside promotes Nrf2 nuclear translocation by competitively binding to Keap1. Sweroside also inhibits oxidative stress and NLRP3-mediated pyroptosis by activating Nrf2, inhibits NF-κB inflammatory pathway by activating SIRT1, and promotes autophagy and induces caspase-dependent apoptosis via the AMPK/mTOR pathway. Sweroside has antioxidant, anti-inflammatory, anti-apoptotic, and lipid metabolism regulating activities, and can be used in the research of myocardial ischemia-reperfusion injury, leukemia, acute lung injury, non-alcoholic fatty liver disease, and other fields.

分子量

358.34

Formula

C₁₆H₂₂O₉
CAS 号
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Sweroside (Standard) 相关分类

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sweroside (Standard)14215-86-2PARPAutophagyKeap1-Nrf2NF-κBNOD-like Receptor (NLR)Reference StandardsSirtuinPyroptosisApoptosisAMPKpoly ADP ribose polymerase Nuclear factor-κBNuclear factor-kappaBAMP-activated protein kinaseInhibitorinhibitorinhibit

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