2. Metabolic Enzyme/Protease Anti-infection
  3. HSV Cathepsin SARS-CoV
  4. Z-L(D-Val)G-CHN2

Z-L(D-Val)G-CHN2 

目录号: HY-108137A 纯度: 99.35% ee.: 100.00%
COA 产品使用指南

摩尔计算器

Z-L(D-Val)G-CHN2 是 Z-LVG-CHN2 (HY-108137) 是异构体，这是一种细胞内不可逆的半胱氨酸蛋白酶 (cysteine proteinase) 抑制剂。Z-LVG-CHN2 是一种三肽衍生物，模拟人半胱氨酸蛋白酶结合中心的一部分。Z-LVG-CHN2 对 HSV 有抑制作用，但对脊髓灰质炎病毒复制无显著影响。通过抑制 SARS-COV-2 的 3CL pro 蛋白酶，Z-LVG-CHN2 有效地抑制 SARS-COV-2 活性 (EC50=190 nM)。

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Z-L(D-Val)G-CHN2 Chemical Structure

Z-L(D-Val)G-CHN2 Chemical Structure

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规格 价格 是否有货 数量
5 mg ￥1850
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Other Forms of Z-L(D-Val)G-CHN2:

Z-L(D-Val)G-CHN2 相关抗体

Top Publications Citing Use of Products

查看 Cathepsin 亚型特异性产品:

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Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Z-L(D-Val)G-CHN2 is the isoform of Z-LVG-CHN2 (HY-108137). Z-LVG-CHN2 is a cell-permeable and irreversible inhibitor of cysteine proteinase. Z-LVG-CHN2 is a tripeptide derivative and mimics part of the human cysteine proteinase-binding center. Z-LVG-CHN2 displays an inhibition on HSV whereas no significant effect on poliovirus replication. Z-LVG-CHN2 effectively blocks SARS-COV-2 replication (EC50=190 nM) via inhibition of SARS-COV-2 3CL pro protease[3].

分子量

445.51

Formula

C22H31N5O5
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Z-L(D-Val)G-CHN2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-L(D-Val)G-CHN2HSVCathepsinSARS-CoVHerpes simplex virusSARS coronaviruscysteine proteinaseSAR-COV-23CL pro proteasemimicInhibitorinhibitorinhibit

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目录号：
HY-108137A
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