Cathepsin Inhibitors

Cathepsin B

Cathepsin C

Cathepsin D

Cathepsin E

Cathepsin K

Cathepsin L

Cathepsin S

Cathepsin Inducers, Inhibitors & Antagonists

Product Name	Cathepsin B	Cathepsin C	Cathepsin D	Cathepsin E	Cathepsin K	Cathepsin L	Cathepsin S	Purity
CA-074 methyl ester	Cathepsin B							99.15%
Calpeptin					cathepsin K			≥98.0%
Z-FY-CHO						cathepsin L
LY 3000328							cathepsin S	98.00%
Odanacatib					cathepsin K			99.82%
SID 26681509						cathepsin L		98.70%
Z-FA-FMK	Cathepsin B					cathepsin L		98.54%
Balicatib	Cathepsin B, IC₅₀: 61 nM				cathepsin K, IC₅₀: 22 nM	cathepsin L, IC₅₀: 48 nM	cathepsin S, IC₅₀: 2900 nM	98.00%
Petesicatib							cathepsin S	99.71%
Z-WEHD-FMK	Cathepsin B							≥98.0%
LHVS	Cathepsin B				cathepsin K	cathepsin L	cathepsin S	99.87%
GSK-2793660		Cathepsin C						99.66%
L-006235	Cathepsin B				cathepsin K			99.96%
Cathepsin L-IN-2	Cathepsin B					cathepsin L		98.27%
Cathepsin C-IN-5		Cathepsin C
Hepcidin-1 (mouse) (TFA)					cathepsin K			98.94%
3-Epiursolic Acid						cathepsin L, IC₅₀: 6.5 μM		99.49%
Relacatib					cathepsin K	cathepsin L		99.99%
ONO-5334					cathepsin K			99.83%
Aurantiamide acetate						cathepsin L		99.60%
RO5461111							human Cathepsin S, IC₅₀: 0.4 nM murine Cathepsin S, IC₅₀: 0.5 nM	98.17%
Gü2602					cathepsin K			98.13%
Z-Phe-Tyr(tBu)-diazomethylketone						cathepsin L		≥99.0%
Hepcidin-1 (mouse)					cathepsin K
MIV-247							cathepsin S
Cathepsin D and E FRET Substrate			Cathepsin D	Cathepsin E
Cathepsin K inhibitor 3					cathepsin K, IC₅₀: 0.5 nM
FGA146						cathepsin L, Ki: 0.87 μM
Cathepsin L-IN-4						cathepsin L
Cathepsin L/S-IN-1						cathepsin L, IC₅₀: 4.10 μM	cathepsin S, IC₅₀: 1.79 μM
JNJ 10329670							cathepsin S, Ki: 34 nM
ASPER-29						cathepsin L, IC₅₀: 6.03 μM	cathepsin S, IC₅₀: 5.02 μM
SPR38	Cathepsin B, IC₅₀: 11.1 ± 1.2 μM					cathepsin L, IC₅₀: 1.92 ± 0.1 μM
ABP 25					cathepsin K
Cathepsin C-IN-3		Cathepsin C
Cathepsin C-IN-4		Cathepsin C
Ac-Glu-Asp(EDANS)-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Gly-Lys(DABCYL)-Glu-NH2			Cathepsin D
Z-Arg-Arg-4MβNA triacetate	Cathepsin B
Ac-Leu-Val-Lys-Aldehyde	Cathepsin B, IC₅₀: 4 nM
Mpro/Cathepsin L-IN-1						cathepsin L
Z-Phe-Phe-Diazomethylketone						cathepsin L
Ac-VLPE-FMK	Cathepsin B					cathepsin L		≥99.0%
FGA145	Cathepsin B, Ki: 206 nM					cathepsin L, Ki: 53 nM
SARS-CoV-2-IN-77						cathepsin L, Ki: 111 nM	cathepsin S, Ki: 103 nM
SQ 32602				Cathepsin E, IC₅₀: 88 nM

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