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  4. (1R,2R)-Calhex 231 hydrochloride

(1R,2R)-Calhex 231 hydrochloride 

目录号: HY-103320B 纯度: 99.07%
COA 产品使用指南

摩尔计算器

(1R,2R)-Calhex 231 hydrochloride 是 Calhex 231 hydrochloride (HY-103320A) 的异构体，可作为实验中的对照化合物。Calhex 231 hydrochloride 是一种通过负变构调节来抑制 CaSR 的。Calhex 231 hydrochloride 在 HEK293 细胞中阻断 Ca2+ 诱导的肌醇磷酸酯的积累，IC50 为 0.39 μM。Calhex 231 hydrochloride 可用于糖尿病性心肌病 (DCM) 的研究。

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(1R,2R)-Calhex 231 hydrochloride Chemical Structure

(1R,2R)-Calhex 231 hydrochloride Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥410
In-stock
5 mg ￥950
In-stock
10 mg ￥1500
In-stock
25 mg ￥2900
In-stock
50 mg ￥4600
In-stock
100 mg ￥6900
In-stock
200 mg   询价  
500 mg   询价  

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Other Forms of (1R,2R)-Calhex 231 hydrochloride:

(1R,2R)-Calhex 231 hydrochloride 相关抗体

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生物活性

(1R,2R)-Calhex 231 hydrochloride is the isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment[1][2].

分子量

443.41

Formula

C25H28Cl2N2O
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

(1R,2R)-Calhex 231 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(1R,2R)-Calhex 231OthersDiabeticcardiomyopathyfibrosisG-proteinα-SMATGF-β1ItchcollagennegativeallostericinositolInhibitorinhibitorinhibit

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目录号：
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