1. Cell Cycle/DNA Damage Others
  2. DNA/RNA Synthesis Biochemical Assay Reagents
  3. 8-Bromoadenine

8-Bromoadenine  (Synonyms: 8-Bromo-9H-purin-6-amine)

目录号: HY-W076740
产品使用指南

8-Bromoadenine (8-Bromo-9H-purin-6-amine) 是 DNA 放射增敏剂,可抑制细胞中 DNA 单链断裂修复。8-Bromoadenine 是腺嘌呤的溴化衍生物,可通过氘取代溴,制备放射性腺嘌呤。

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8-Bromoadenine Chemical Structure

8-Bromoadenine Chemical Structure

CAS No. : 6974-78-3

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规格 价格 是否有货 数量
25 mg ¥266
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50 mg ¥420
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100 mg ¥630
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

8-Bromoadenine (8-Bromo-9H-purin-6-amine) is a DNA radiosensitizer that inhibits DNA single-strand break repair in cells. 8-Bromoadenine is a brominated derivative of adenine, and radioactive adenine can be prepared by replacing bromine with deuterium[1][2].

体外研究
(In Vitro)

8-Bromoadenine (0.1 mM; 30-90 min) 能抑制 HeLa-M 细胞单层培养物中的 DNA 单链断裂修复。且经 γ 照射后,细胞合成的 DNA 的质量比无嘌呤添加时细胞合成的 DNA 治疗更低[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

214.02

Formula

C5H4BrN5

CAS 号
性状

固体

中文名称

8-溴腺嘌呤

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
8-Bromoadenine
目录号:
HY-W076740
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