2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. BMY-25271

BMY-25271 是一个组胺 H2 受体 (histamine H2 receptor) 拮抗剂。

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BMY-25271 Chemical Structure

BMY-25271 Chemical Structure

CAS No. : 78441-82-4

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BMY-25271 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

BMY-25271 is a histamine H2 receptor antagonist.

IC50 & Target

Histamine H2 receptor[1]
体内研究
(In Vivo)

BMY-25271 is a histamine H2 receptor antagonist. The dose response curves are parallel and oral ED50 values derived from probit analysis are 0.093, 0.97 and 6.9 mg/kg for BMY-25271, ranitidine and cimetidine, respectively. BMY-25271, therefore, is about 10 and 74 times more potent than ranitidine and cimetidine, respectively. Pretreatment with the highest dose of BMY-25271 does not significantly affect the absorption of aspirin or the formation of its major metabolite, salicylic acid[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

329.44

Formula

C12H19N5O2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献
Animal Administration
[1]

Five beagle dogs are used in this study. Vehicle or BMY-25271 (0.4 mg/kg) is administered orally 1 h before aspirin (100 mg/kg). Blood samples are collected from the jugular vein just before aspirin administration and 30, 60, 90 and 120 min after aspirin administration. One week later, the dogs are crossed over, and the study is repeated[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

BMY-25271 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMY-2527178441-82-4BMY25271BMY 25271Histamine ReceptorInhibitorinhibitorinhibit

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产品名称：
BMY-25271
目录号：
HY-100191
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