1. Anti-infection
  2. HCV

Cyclophilin inhibitor 1 

目录号: HY-112712
产品使用指南

Cyclophilin inhibitor 1 是一种有效、可口服的亲环素 A (cyclophilin A) 抑制剂,Kd 值为 5 nM,具有抗 HCV 活性,对 HCV 2a 的 EC50 值为 98 nM。

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Cyclophilin inhibitor 1 Chemical Structure

Cyclophilin inhibitor 1 Chemical Structure

CAS No. : 1509904-96-4

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Description

Cyclophilin inhibitor 1 is a potent and orally bioavailable cyclophilin A inhibitor, with a Kd of 5 nM, shows effective anti-HCV activity, with an EC50 of 98 nM for HCV 2a[1].

IC50 & Target

Kd: 5 nM (Cyclophilin A)[1]
EC50: 98 nM (HCV 2a)[1]

In Vitro

Cyclophilin inhibitor 1 (Compound 3) inhibits HCV 2a activity, with an EC50 of 98 nM[1].

References
Molecular Weight

593.67

Formula

C₃₁H₃₉N₅O₇

CAS No.

1509904-96-4

SMILES

C[C@@H](NC([C@@H]1CCCN(C([C@H](C)NC([C@H](C(C)C)OC2=O)=O)=O)N1)=O)C3=CC=C4C(C=C(/C=C/C52COCOC5)C=C4)=N3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Cyclophilin inhibitor 1
目录号:
HY-112712
需求量:

Cyclophilin inhibitor 1

Cat. No.: HY-112712