1. Membrane Transporter/Ion Channel
  2. TRP Channel
  3. GSK3395879

GSK3395879 

目录号: HY-112202
产品使用指南

GSK3395879 是一种口服生物可利用的选择性瞬时受体电位香草醛-4 (TRPV4) 拮抗剂,作用于 hTRPV4,IC50 为 1 nM。

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GSK3395879 Chemical Structure

GSK3395879 Chemical Structure

CAS No. : 2215852-91-6

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Description

GSK3395879 is a selective and orally bioavailable transient receptor potential vanilloid-4 (TRPV4) antagonist with an IC50 of 1 nM for hTRPV4[1].

IC50 & Target

IC50: 1 nM (hTRPV4)[1]

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

485.41

Formula

C₂₀H₁₅F₄N₃O₅S

CAS No.

2215852-91-6

SMILES

FC1=C(C#N)C=CC(O[C@@H]2[C@@](CO)(O)CN(S(C3=C(C#N)C=C(C(F)(F)F)C=C3)(=O)=O)C2)=C1

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
GSK3395879
目录号:
HY-112202
需求量:

GSK3395879

Cat. No.: HY-112202