1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK
  3. JAK-IN-3

JAK-IN-3 

目录号: HY-111750
产品使用指南

JAK-IN-3 (compound 22) 是一种有效的 JAK 抑制剂,其对 JAK3、JAK1、TYK2 和JAK2 的 IC50 值分别为 3 nM、5 nM、34 nM 和 70 nM。

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JAK-IN-3 Chemical Structure

JAK-IN-3 Chemical Structure

CAS No. : 1400876-94-9

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Description

JAK-IN-3 (compound 22) is a potent JAK inhibitor, with IC50 values of 3 nM, 5 nM, 34 nM and 70 nM for JAK3, JAK1, TYK2 and JAK2, respectively[1].

IC50 & Target[1]

JAK3

3 nM (IC50)

JAK1

5 nM (IC50)

Tyk2

34 nM (IC50)

JAK2

70 nM (IC50)

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

340.38

Formula

C₁₈H₂₀N₄O₃

CAS No.

1400876-94-9

SMILES

O=C(C1=C(N[C@@H]([C@H](O)C)CO)C2=CC(C3=CC=CC=C3)=CN2N=C1)N

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
JAK-IN-3
目录号:
HY-111750
需求量:

JAK-IN-3

Cat. No.: HY-111750