2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 疾病相关化合物库
  6. 抗肥胖化合物库
抗肥胖化合物库 - Anti-Obesity Compound Library

Cat. No.: HY-L087

肥胖已经成为了全世界的公共卫生问题，并与许多慢性疾病有关，包括骨关节炎、阻塞性睡眠呼吸暂停、胆结石、脂肪肝、生殖和胃肠道癌症、血脂异常、高血压、2型糖尿病、心力衰竭、冠状动脉疾病、和中风等。肥胖被认为是食欲调节和能量代谢两种生理功能失调导致的疾病，这两种功能失调结合在一起导致能量平衡失调。因此，开发针对新途径的肥胖治疗药物是生物制药行业日益关注的焦点。

MCE抗肥胖化合物库包含 2338 种化合物，主要靶向食欲控制、脂肪代谢及能量消耗等相关信号通路，是开发抗肥胖药物的有用工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗肥胖化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，2290 个产品以 10 mM 浓度提供，45 个产品以 2 mM 浓度提供，3 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +
联系专家定制

Compound Screening Libraries

Download
相关产品推荐

Top Publications Citing Use of MCE Products

View More

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 2338 obesity related compounds.

•   The major targets include Fatty Acid Synthase, DGAT, Acetyl-CoA Carboxylas, MCHR1 (GPR24), Stearoyl-CoA Desaturase (SCD), etc..

•   A useful tool for the discovery of anti-obesity drugs.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 2338 anti-obesity compounds supplied as pre-dissolved Solutions or Solid.
Solution: 2290 compounds supplied in 10 mM solution, 45 compounds supplied in 2 mM solution, 3 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

NF-κB (233)

EGFR (182)

PI3K (181)

JAK (117)

Akt (106)

STAT (98)

mTOR (91)

PPAR (81)

ERK (75)

GSK-3 (69)

AMPK (56)

Raf (55)

MEK (42)

CDK (40)

VEGFR (37)

COX (35)

JNK (35)

Wnt (29)

DYRK (28)

Pim (23)

MAP3K (21)

SGLT (20)

FLT3 (17)

MAP4K (17)

MMP (17)

Src (17)

HIV (14)

PI4K (14)

PDGFR (11)

FGFR (10)

PDK-1 (10)

FXR (9)

HDAC (9)

FAK (8)

PKC (8)

Btk (7)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

* Container：

       留言给我们：

    Bulk Inquiry

    Inquiry Information

    产品名称：
    Anti-Obesity Compound Library
    目录号：
    HY-L087
    需求量：

    Request for SDF File

    Please fill out this form to request the SDF file. We will send it to your Email address shortly.

    Your information is safe with us. * Required Fields.

       产品名称：

    		  

    * 客户姓名：

    * Email：

    		 

    * 公司或机构名称：

    * 电话：

    		     

       留言给我们：

    Request for SDF File

    We have received your request and will respond to you as soon as possible.

    嗨！很高兴为您提供帮助！

    尊敬的 MCE 客户您好，
    请您选择所在区域，我们将转接对应客服为您服务！

    热门区域

    A

    B

    C

    F

    G

    H

    J

    L

    N

    Q

    S

    T

    X

    Y

    Z

    热 A B C F G H J L N Q S T X Y Z