1. Quinones

Physcion (Synonyms: Parietin; Rheochrysidin)

目录号: HY-N0108
产品使用指南

Physcion (Parietin) 是从中药大黄中得到的蒽醌类物质,为 6-磷酸葡萄糖酸脱氢酶 (6-phosphogluconate dehydrogenase) 抑制剂,IC50Kd 值分别为 38.5 μM 和 26.0 μM。Physcion (Parietin) 具有通便、保肝、抗炎、抗菌、抗增殖、抗肿瘤作用。

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Physcion Chemical Structure

Physcion Chemical Structure

CAS No. : 521-61-9

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Description

Physcion (Parietin) is an anthraquinone isolated from traditional Chinese medicine Radix et Rhizoma Rhei, acts as an inhibitor of 6-phosphogluconate dehydrogenase, with an IC50 and a Kd of 38.5 μM and 26.0 μM, respectively[1][2]. Physcion (Parietin) exhibits laxative, hepatoprotective, anti-inflammatory, anti-microbial, anti-proliferative and anti-tumor effects[2].

IC50 & Target

IC50: 38.5 μM (6-phosphogluconate dehydrogenase)[1]
Kd: 26.0 μM (6-phosphogluconate dehydrogenase)[1]

References
Molecular Weight

284.26

Formula

C₁₆H₁₂O₅

CAS No.

521-61-9

SMILES

O=C1C2=C(C=C(C)C=C2O)C(C3=CC(OC)=CC(O)=C13)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Physcion
目录号:
HY-N0108
需求量:

Physcion

Cat. No.: HY-N0108