1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease

Ser/Thr Protease

Serine proteases are enzymes that cleave peptide bonds in proteins, in which serine serves as the nucleophilic amino acidat the active site. They are found ubiquitously in both eukaryotes and prokaryotes. Serine proteases fall into two broad categories based on their structure: chymotrypsin-like or subtilisin-like. In humans, serine proteases are responsible for co-ordinating various physiological functions, including digestion, immune response, blood coagulation and reproduction. Threnonine proteases are a family of proteolytic enzymes harbouring a threonine (Thr) residue within the active site. The prototype members of this class of enzymes are the catalytic subunits of the proteasome, however the acyltransferases convergently evolved the same active site geometry andmechanism.

Ser/Thr Protease 相关产品 (7):

Cat. No. Product Name Effect Purity
  • HY-100877
    GCN2-IN-1 Inhibitor >98.0%
    GCN2-IN-1 是一种有效的一般性调控阻遏蛋白激酶 2 (GCN2) 抑制剂,在酶和细胞检测中 IC50 都 < 0.3 μM。
  • HY-B0190A
    Nafamostat mesylate Inhibitor
    Nafamostat甲磺酸盐是广谱的丝氨酸蛋白酶抑制剂,血管舒缓素抑制剂,能抑制血液凝固,还是潜在的补体抑制剂。
  • HY-16511
    Upamostat Inhibitor >98.0%
    Upamostat 是一种丝氨酸蛋白酶抑制剂。Upamostat 是具有口服活性的 WX-UK1 前药,是一种尿激酶型纤溶酶原激活剂 (uPA) 抑制剂。
  • HY-101214
    UK-371804 Inhibitor >98.0%
    UK-371804是尿嘧啶型纤溶酶原激活物 (uPA) 的抑制剂,Ki值为10 nM。
  • HY-B0190
    Nafamostat Inhibitor
    Nafamostat是广谱的丝氨酸蛋白酶抑制剂,血管舒缓素抑制剂,能抑制血液凝固,还是潜在的补体抑制剂。
  • HY-B0190B
    Nafamostat hydrochloride Inhibitor
    Nafamostat盐酸盐是广谱的丝氨酸蛋白酶抑制剂,血管舒缓素抑制剂,能抑制血液凝固,还是潜在的补体抑制剂。
  • HY-U00346
    DPP-IV-IN-1 Inhibitor
    DPP-IV-IN-1 是一种有效的 dipeptidyl peptidase IV (DPP-IV) 抑制剂,IC50 值为 4.6 nM;DPP-IV 为一种特异性的丝氨酸蛋白酶 (serine protease)。
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