2. Neuronal Signaling Metabolic Enzyme/Protease
  3. Cholinesterase (ChE) Phosphodiesterase (PDE)
  4. AChE/PDE4-IN-1

AChE/PDE4-IN-1 (化合物 12c) 是一种有效和选择性的双重 PDE4/AChE 抑制剂，抑制 AChE 和 PDE4D 的 IC50 值分别为 0.28 μM 和 1.88 μM。AChE/PDE4-IN-1 在阿尔茨海默病的研究中具有抗神经炎症作用。

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AChE/PDE4-IN-1 Chemical Structure

AChE/PDE4-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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AChE/PDE4-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AChE/PDE4-IN-1 (compound 12c) is a potent and selective dual PDE4/AChE inhibitor, with IC50s of 0.28 μM and 1.88 μM for AChE and PDE4D, respectively. AChE/PDE4-IN-1 exhibits anti-neuroinflammatory effect for the research of Alzheimer's disease[1].

IC50 & Target[1]

AChE

0.28 μM (IC50)

PDE4

1.88 μM (IC50)

分子量

380.48

Formula

C23H28N2O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AChE/PDE4-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AChE/PDE4-IN-1Cholinesterase (ChE)Phosphodiesterase (PDE)anti-neuroinflammatoryAlzheimer's diseaseInhibitorinhibitorinhibit

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