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  3. AICAR-13C2,15N

AICAR-13C2,15N  (Synonyms: 阿卡地新-13C2,15N; Acadesine-13C2,15N; AICA Riboside-13C2,15N)

目录号: HY-13417S
产品使用指南

AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N) 是 13C 和 15N 标记的 AICAR (HY-13417)。AICAR (Acadesine) 是一种腺苷类似物和 AMPK 激活剂。AICAR 调节葡萄糖和脂质代谢,并抑制促炎细胞因子和 iNOS 产生。AICAR 也是一种自噬YAP线粒体自噬抑制剂[3]

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AICAR-<sup>13</sup>C<sub>2</sub>,<sup>15</sup>N Chemical Structure

AICAR-13C2,15N Chemical Structure

CAS No. : 1609374-70-0

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Other Forms of AICAR-13C2,15N:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AICAR-13C2,15N (Acadesine-13C2,15N; AICA Riboside-13C2,15N)is the 13C and 15N labeledAICAR(HY-13417)[1]. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[2][3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

261.21

Formula

C713C2H14N315NO5

CAS 号
中文名称

阿卡地新-13C2,15N

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

AICAR-13C2,15N 相关分类

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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AICAR-13C2,15N
目录号:
HY-13417S
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