2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. Aldicarb sulfoxide

Aldicarb sulfoxide 是 Aldicarb 的代谢产物。Aldicarb sulfoxide 影响 CHO-K1 细胞中的谷胱甘肽相关酶。Aldicarb sulfoxide 在斑马鱼中抑制胆碱酯酶 (ChE) 和羧酸酯酶 (CaE)，IC50 均为 10 μM。

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Aldicarb sulfoxide Chemical Structure

Aldicarb sulfoxide Chemical Structure

CAS No. : 1646-87-3

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10 mg ￥1836
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Aldicarb sulfoxide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Aldicarb sulfoxide is a metabolite of Aldicarb. Aldicarb sulfoxide affects the glutathione-linked enzymes in CHO-K1 cells. Aldicarb sulfoxide inhibits cholinesterase (ChE) and carboxylesterase (CaE) with IC50 of 10 μM for both in zebrafish[1][2].

IC50 & Target

IC50: 10 μM (zebrafish ChE); IC50: 10 μM (zebrafish CaE)[2]
体外研究
(In Vitro)

Aldicarb sulfoxide (10 μg/ml; 24 h) decreases the glutathione (GSH) concentration in CHO-K1 cells by 13.34%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione reductase (GR) activity in CHO-K1 cells by 101%[1].
Aldicarb sulfoxide (10 μg/ml; 24 h) increases glutathione peroxidase (GPx) activity increased in CHO-K1 cells by 32%[1].
Aldicarb sulfoxide (0.2-300 μM, 48 h) induces the increase of heart rate at low and decrease at higher concentration in zebrafish embryos[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Aldicarb sulfoxide 相关抗体:
分子量

206.26

Formula

C7H14N2O3S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Aldicarb sulfoxide 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aldicarb sulfoxide1646-87-3Drug MetabolitemetaboliteAldicarbglutathionezebrafishCHO-K1Inhibitorinhibitorinhibit

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