2. GPCR/G Protein Neuronal Signaling
  3. MCHR1 (GPR24)
  4. AMG-076

AMG-076 是一种具有口服活性的，选择性 MCHR1 拮抗剂。AMG-076 可显着降低高脂饮食喂养的非肥胖小鼠和高脂饮食诱导的肥胖 (DIO) 小鼠的体重增加。

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AMG-076 Chemical Structure

AMG-076 Chemical Structure

CAS No. : 1001438-96-5

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AMG-076 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AMG-076 is an orally bioavailable and selective MCHR1 antagonist. AMG-076 results in significant reduction in body weight gain in nonobese mice fed a high-fat diet and in high-fat diet-induced obese (DIO) mice[1].

分子量

620.72

Formula

C32H39F3N2O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

AMG-076 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AMG-0761001438-96-5AMG076AMG 076MCHR1 (GPR24)Melanin concentrating hormone receptor 1OrallyMCHR1nonobesehigh-fat dietobeseDIOInhibitorinhibitorinhibit

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产品名称：
AMG-076
目录号：
HY-101699A
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