1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. AmmTX3

AmmTX3 是一种肽毒素,可以从蝎子 Androctonus mauretanicus 的毒液中分离出来。AmmTX3 是 Kv4 通道的特异性阻断剂。AmmTX3 抑制 A 型 K+ 电流 (Ki: 131 nM)。

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Custom Peptide Synthesis

AmmTX3 Chemical Structure

AmmTX3 Chemical Structure

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规格 是否有货
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Other Forms of AmmTX3:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

AmmTX3 is a peptide toxin that can be isolated from the venom of the scorpion Androctonus mauretanicus. AmmTX3 is specific blocker of Kv4 channel. AmmTX3 inhibits the A-type K+ current (Ki: 131 nM)[1][2].

IC50 & Target

Kv4 channel[2]

分子量

3822.47

Formula

C158H262N50O48S6

Unlabeled CAS

Sequence

{Glp}-Ile-Glu-Thr-Asn-Lys-Lys-Cys-Gln-Gly-Gly-Ser-Cys-Ala-Ser-Val-Cys-Arg-Lys-Val-Ile-Gly-Val-Ala-Ala-Gly-Lys-Cys-Ile-Asn-Gly-Arg-Cys-Val-Cys-Tyr-Pro (Disulfide bonds:Cys8-Cys28, Cys13-Cys33 and Cys17-Cys35)

Sequence Shortening

{Glp}-IETNKKCQGGSCASVCRKVIGVAAGKCINGRCVCYP (Disulfide bonds:Cys8-Cys28, Cys13-Cys33 and Cys17-Cys35)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
AmmTX3
目录号:
HY-P1426
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