2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Anticancer agent 198

Anticancer agent 198 (compound 18b) 是有效的抗癌剂和潜在的 WRN 蛋白抑制剂。Anticancer agent 198 对 K562 细胞和 WRN 过表达的 PC3 细胞的毒性显著。

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Anticancer agent 198 Chemical Structure

Anticancer agent 198 Chemical Structure

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Anticancer agent 198 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

Anticancer agent 198 (compound 18b) is a potent anticancer agent and potential WRN protein inhibitor. Anticancer agent 198 was significantly toxic to K562 cells and WRN-overexpressing PC3 cells[1].

体外研究
(In Vitro)

Anticancer agent 198 显著抑制 PC3-WRN 细胞的存活，在 PC3-WRN (OE) 细胞和 PC3 细胞间 IC20 分别为 0.12 μM 和 0.98 μM[1].
Anticancer agent 198 (5 μM) 对几种癌细胞系的 IC50s 分别为 >10 μM (PC3 细胞)，0.05 μM (K562 细胞)，1.1 μM (293T 细胞)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Anticancer agent 198 相关抗体:
分子量

451.47

Formula

C25H23F2N3O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Anticancer agent 198 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anticancer agent 198Anticancer agent198Anticancer agent-198DNA/RNA SynthesisInhibitorinhibitorinhibit

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