2. Anti-infection
  3. Parasite
  4. Antileishmanial agent-16

Antileishmanial agent-16 (化合物 14c) 是一种抗利什曼原虫 (Leishmania) 剂。Antileishmanial agent-16 具有优越的抗 Leishmania major 前鞭毛体活性 (IC50 = 0.59 µM) 和抗 Leishmania major 无鞭毛体活性 (IC50 = 0.81 µM)。Antileishmanial agent-16 对哺乳动物细胞（VERO 细胞）具有较好的安全性。

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Antileishmanial agent-16 Chemical Structure

Antileishmanial agent-16 Chemical Structure

CAS No. : 2934738-41-5

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Antileishmanial agent-16 相关抗体

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 µM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 µM). Antileishmanial agent-16 has good safety to mammalian cells (VERO cells)[1].

IC50 & Target

Leishmania[1].
体外研究
(In Vitro)

Antileishmanial agent-16 (0-20 µM; 24 h) 显示出优越的抗 L. Major 前鞭毛体和无鞭毛体活性，其 IC50 值分别为 0.59 和 0.81 µM[1]。
Antileishmanial agent-16 显示出对 L. amastigote 的高选择性及其对哺乳动物细胞（VERO 细胞）的安全性，SI 值为 311.4[1]。
选择性指数 (SI)：体外细胞毒性（CC50，单位为 μM）与抗利什曼原虫无鞭毛体活性（IC50，单位为 μM）之比。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antileishmanial agent-16 相关抗体:

Cell Viability Assay[1]

Cell Line: Promastigote and amastigote forms of Leishmania major strain
Concentration: 0-20 µM
Incubation Time: 24 h
Result: Inhibited L. Major promastigote and amastigote forms, with IC50s of 0.59 and 0.81 µM, respectively.
分子量

495.61

Formula

C27H37N5O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antileishmanial agent-16 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antileishmanial agent-162934738-41-5Antileishmanial agent16Antileishmanial agent 16ParasiteL. MajorVEROpromastigotesamastigotesInhibitorinhibitorinhibit

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