2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. Antitumor agent-127

Antitumor agent-127 (compound 1) 是一种亲本大环肽。Antitumor agent-127 在 786-O 和 MDA-MB-231 肿瘤细胞系中表现出与 ROR1 的纳摩尔细胞结合和相对良好的内化。

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Antitumor agent-127 Chemical Structure

Antitumor agent-127 Chemical Structure

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Antitumor agent-127 相关抗体

Top Publications Citing Use of Products

查看 ROR 亚型特异性产品:

查看所有亚型
RORγ RORα RORβ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Antitumor agent-127 (compound 1) is a parent macrocyclic peptide. Antitumor agent-127 displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines[1].

体外研究
(In Vitro)

Antitumor agent-127 (compound 1) 不会诱导 Mia PaCa-2 细胞凋亡，Mia PaCa-2 细胞是一种模型胰腺肿瘤细胞系，细胞表面 ROR1 表达水平相对较低[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Antitumor agent-127 相关抗体:
分子量

1670.92

Formula

C86H107N15O18S
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Antitumor agent-127 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antitumor agent-127Antitumor agent127Antitumor agent 127RORRAR-related orphan receptor786-OMDA-MB-231Inhibitorinhibitorinhibit

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