2. Neuronal Signaling Membrane Transporter/Ion Channel
  3. Serotonin Transporter Sodium Channel
  4. Atomoxetine

Atomoxetine  (Synonyms: 托莫西汀; Tomoxetine; (R)-Tomoxetine)

目录号: HY-107370
产品使用指南

摩尔计算器

Atomoxetine (Tomoxetine) 是一种选择性去甲肾上腺素再摄取抑制剂 (noradrenaline reuptake)，去甲肾上腺素 (NE)、5-羟色胺 (5-HT) 和多巴胺 (DA) 转运体的 Ki 值分别为 5、77 和 1451 nM。Atomoxetine (Tomoxetine) 可以增加 PFC 中 DAEX 和 NEEX，从而增强儿茶酚胺能神经传递。Atomoxetine (Tomoxetine) 是一种有效的Na+ 通道阻断剂 (VGSCs)。Atomoxetine (Tomoxetine) 可用于注意力缺陷多动障碍 (ADHD) 的研究。

在相同的摩尔浓度下，化合物盐形式与游离形式有相同的生物活性，但盐形式 Atomoxetine hydrochloride 通常具有更好的水溶性和稳定性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Atomoxetine Chemical Structure

Atomoxetine Chemical Structure

CAS No. : 83015-26-3

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Atomoxetine 的其他形式现货产品:

Customer Review

Other Forms of Atomoxetine:

Atomoxetine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Atomoxetine (Tomoxetine) is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine (Tomoxetine) increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine (Tomoxetine) is a potent Na+ channels (VGSCs) blocker. Atomoxetine (Tomoxetine) can be used for attention-deficit hyperactivity disorder (ADHD) research[1][2][3].

体外研究
(In Vitro)

Atomoxetine (Tomoxetine) (1-100 µM; 0.5-20 seconds; tsA201 cells) interacts with the human heart muscle sodium channel (hNav1.5) in a state and dose-dependent manner[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Atomoxetine 相关抗体:
体内研究
(In Vivo)

Atomoxetine (Tomoxetine) (0.3-3 mg/kg; i.p.; 0-4 hours; male Sprague-Dawley rats) increases extracellular norepinephrine and dopamine by 3-fold and increases Fos expression in the rat prefrontal cortex[1].
Atomoxetine (Tomoxetine) (0.1-5 mg/kg; i.p. and p.o; for 14 days; spontaneously hypertensive rat) can improve behaviors associated with ADHD in rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats[1]
Dosage: 0.3, 1 and 3 mg/kg
Administration: Intraperitoneal injection; for 4 hours
Result: Increased the number of cells expressing Fos-like immunoreactivity in PFC 3.7-fold and increased extracellular norepinephrine and dopamine by 3-fold.
Animal Model: Spontaneously hypertensive rat (SHR)[3]
Dosage: 0.1, 0.3, 1.25 and 5.0 mg/kg
Administration: Intraperitoneal injection and oral administration; for 14 days
Result: Had non-impact on the measurement of motor activity.
Clinical Trial
分子量

255.35

Formula

C17H21NO
CAS 号
中文名称

托莫西汀
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Atomoxetine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Atomoxetine83015-26-3Tomoxetine (R)-Tomoxetine托莫西汀Serotonin TransporterSodium Channel5-HTTSERTSLC6A4Na channelsNa+ channelsVGSCsnoradrenalinecatecholaminergicdopamineserotoninInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Atomoxetine
目录号：
HY-107370
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z