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  3. ATX inhibitor 16

ATX inhibitor 16 是一种有效的 ATX 抑制剂,IC50 为 0.0021 µM。ATX inhibitor 16 在乳腺癌细胞中显示出优异的抗增殖活性。

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ATX inhibitor 16 Chemical Structure

ATX inhibitor 16 Chemical Structure

CAS No. : 2484811-36-9

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  • 生物活性

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生物活性

ATX inhibitor 16 is a potent ATX inhibitor with an IC50 of 0.0021 µM. ATX inhibitor 16 shows excellent anti-proliferative activities in breast cancer cells[1].

IC50 & Target

IC50: 0.0021 µM (ATX)[1]

体外研究
(In Vitro)

ATX inhibitor 16 (compound 9j) (0-15 µM; 72 h) shows excellent anti-proliferative activities in breast cancer cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: MCF7, MDA-MB-231, A549, H2228 cells
Concentration: 0-15 µM
Incubation Time: 72 h
Result: Exhibited excellent anti-proliferative activities with IC50s of 0.43, 0.31, 10.98, 7.18 µM for MCF7, MDA-MB-231, A549, H2228 cells, respectively.
分子量

584.68

Formula

C28H27F3N6OS2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

ATX inhibitor 16 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ATX inhibitor 16
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HY-146889
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