1. Biology Dictionary
  2. Type-1-insulin-like growth factor receptor (IGF-1R)

Type-1-insulin-like growth factor receptor (IGF-1R)1 型胰岛素样生长因子受体

释义:

The type 1 insulin-like growth factor receptor (IGF-1R) is a transmembrane glycoprotein composed of two extracellular alpha subunits and two beta subunits with tyrosine kinase activity. The IGF-1R is frequently upregulated in cancers and promotes proliferation and cell survival.

1 型胰岛素样生长因子受体 (IGF-1R) 是一种跨膜糖蛋白,由两个细胞外 α 亚基和两个具有酪氨酸激酶活性的 β 亚基组成。IGF-1R 在癌症中经常上调并促进增殖和细胞存活。

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