1. Membrane Transporter/Ion Channel GPCR/G Protein
  2. P2X Receptor P2Y Receptor
  3. Blue FPG-A trisodium

Blue FPG-A trisodium 是一种选择性的 P2X1 受体和 P2Y1 受体拮抗剂,IC50 值分别为 35.5 μM 和 2.6 μM。Blue FPG-A trisodium 是活性蓝 2 组成成分中的一种结构异构体。

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Blue FPG-A trisodium Chemical Structure

Blue FPG-A trisodium Chemical Structure

CAS No. : 78617-94-4

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2)[1].

IC50 & Target[1]

p2x1 Receptor

35.5 μM (IC50)

P2Y1 Receptor

2.6 μM (IC50)

体外研究
(In Vitro)

Blue FPG-A trisodium (RB 2 para) (1-100 μM) 抑制 α、β-亚甲基 ATP (α、β-MeATP) 诱导的大鼠输精管 (RVD) 收缩和 5’-o-(2-硫代二磷酸腺苷) (ADPβS) 诱导的卡巴胆碱 (Carbachol,HY-B1208) 预处理的豚鼠结肠带 (GPTC) 的松弛[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

840.10

Formula

C29H17ClN7Na3O11S3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Blue FPG-A trisodium
目录号:
HY-D1199
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