2. Immunology/Inflammation
  3. Toll-like Receptor (TLR)
  4. BNT411

BNT411 是一种选择性 TLR7 激动剂，可以在体内和体外诱导 IFNa 释放。BNT411 具有抗癌活性，可以用于癌症的研究 (包括非小细胞肺癌、胰腺癌和未经化疗的广泛期小细胞肺癌 (ES-SCLC))。

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BNT411 Chemical Structure

BNT411 Chemical Structure

CAS No. : 2296821-50-4

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规格 是否有货
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Customer Review

BNT411 相关抗体

Top Publications Citing Use of Products

查看 Toll-like Receptor (TLR) 亚型特异性产品:

查看所有亚型
TLR3 TLR8 TLR9 TLR2 TLR4 TLR7 TLR1 TLR6

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BNT411 is a selective TLR7 agonist that can induce the release of IFNa both in vivo and in vitro. BNT411 has anticancer activity and can be used in cancer research, including non-small cell lung cancer, pancreatic cancer, and untreated extensive-stage small cell lung cancer (ES-SCLC)[1].

体内研究
(In Vivo)

BNT411 (3 mg/kg; 静脉注射; 每隔 4 到 5 天一次，共注射 8 次 ) 在小鼠肿瘤模型中具有抗肿瘤活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

439.55

Formula

C24H33N5O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BNT411 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BNT4112296821-50-4BNT 411BNT-411Toll-like Receptor (TLR)non-small cell lung cancerpancreatic canceruntreated extensive-stage small cell lung cancer (ES-SCLC)Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-160715
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