1. Epigenetics
  2. Epigenetic Reader Domain
  3. BRD-IN-3

BRD-IN-3 

目录号: HY-128597
产品使用指南

BRD-IN-3 ((R,R)-36n) 是一个强效的P300/CBP 相关因子溴端结构域 (PCAF BRD) 的抑制剂,其IC50 值为 7 nM。BRD-IN-3 也能抑制GCN5 和FALZ。

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BRD-IN-3 Chemical Structure

BRD-IN-3 Chemical Structure

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Description

BRD-IN-3 ((R,R)-36n) is a highly potent PCAF bromodomain (BRD) inhibitor, with an IC50 of 7 nM. BRD-IN-3 also exhibits activity against GCN5 and FALZ[1].

IC50 & Target

IC50: PCAF BRD[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

395.45

Formula

C₂₁H₂₅N₅O₃

SMILES

CN(C1)C[C@H](NC(N2C)=NC3=C(NC=C3)C2=O)C[C@@H]1C4=CC=C5OCCOC5=C4

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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