2. Anti-infection
  3. Antibiotic Bacterial
  4. Cefotiam dihydrochloride hydrate

Cefotiam dihydrochloride hydrate  (Synonyms: SCE-963 dihydrochloride hydrate)

目录号: HY-B0734B
产品使用指南

摩尔计算器

Cefotiam (SCE-963) dihydrochloride hydrate 是肠外头孢菌素类抗生素。Cefotiam dihydrochloride hydrate 对革兰氏阳性菌和革兰氏阴性菌具有广谱活性。

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Cefotiam dihydrochloride hydrate Chemical Structure

Cefotiam dihydrochloride hydrate Chemical Structure

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Cefotiam dihydrochloride hydrate 的其他形式现货产品:

Customer Review

Other Forms of Cefotiam dihydrochloride hydrate:

Cefotiam dihydrochloride hydrate 相关抗体

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Aminoglycoside Glycopeptide Lipopeptide Macrolide Oxazolidinone Quinolone Tetracycline β-lactam

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cefotiam (SCE-963) dihydrochloride hydrate is a parenteral cephalosporin antibiotic. Cefotiam dihydrochloride hydrate has broad-spectrum activity against Gram-positive and Gram-negative bacteria[1][2].

IC50 & Target

β-lactam

 

体外研究
(In Vitro)

Cefotiam (SCE-963; 0-6.25 μg/mL; 8 h) dihydrochloride hydrate has antibacterial activity with a MIC value of 1.56 μg/mL for P. mirabilis IFO 3849[1].
Cefotiam (0-6.25 μg/mL; 8 h) dihydrochloride hydrate has highly active against both Staph. aureus (27 strains, MIC values of 0.5-1 μg/mL) and Staph. albus (8 strains, MICs 0.25-0.5 μg/mL). All 29 strains of haemolytic streptococci, 9 strains of pneumococci and 6 strains of Streptococcus viridans with the MIC values of in the range 0.06-4 μg/mL[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cefotiam dihydrochloride hydrate 相关抗体:
体内研究
(In Vivo)

Cefotiam (SCE-963; 12.5-800 mg/kg; i.h.; twice a day for 5 d) dihydrochloride hydrate can cure urinary tract infection with P. mirabilis in mice to reduce or complete eradicate bacteria in the bladder walls and kidneys[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female CF1/b mice with P. mirabilis xenograft[1]
Dosage: 12.5, 25, 50, 100, 200, 400 and 800 mg/kg
Administration: Subcutaneous injection; twice a day, for 5 days
Result: Reduced or complete eradicated bacteria in the bladder walls and kidneys of mice sacrificed the day after treatment was terminated.
Clinical Trial
Formula

C18H25Cl2N9O4S3.xH2O
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cefotiam dihydrochloride hydrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cefotiam dihydrochlorideSCE-963 dihydrochlorideAntibioticBacterialcephalosporin antibioticgram-positive bacteriasgram-negative bacteriasantibacterial activityInhibitorinhibitorinhibit

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