2. Peptides
  3. DC432

DC432 是 N-端甲基转移酶1/2 (NTMT1/2) 的拟肽抑制剂 IC50 为 54 nM。HCT116 能够抑制 HCT116 细胞中 NTMT1/2 底物 N 端甲基化水平，用于 NTMT1/2 探针的研究。

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DC432 Chemical Structure

DC432 Chemical Structure

CAS No. : 2388988-70-1

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DC432 相关抗体

Top Publications Citing Use of Products

  • 生物活性

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  • 参考文献

生物活性

HCT116 is a peptidomimetic inhibitor of N-terminal methyltransferase 1/2 (NTMT1/2) with an IC50 of 54 nM. HCT116 can inhibit the N-terminal methylation level of NTMT1/2 substrates in HCT116 cells, and is used for the study of NTMT1/2 probes.

IC50 & Target

IC50: 54 nM (NTMT1/2)[1].
分子量

1313.56

Formula

C55H100N28O10
CAS 号
Sequence

{p-Hydroxybenzeneacetic acid}-Pro-Lys-Arg-Arg-Arg-Arg-Arg-Arg-NH2
Sequence Shortening

{p-Hydroxybenzeneacetic acid}-PKRRRRRR-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DC4322388988-70-1DC 432DC-432OthersHCT116NTMT1/2probeInhibitorinhibitorinhibit

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产品名称：
DC432
目录号：
HY-P10028
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