1. Anti-infection
  2. Influenza Virus
  3. Eleutheroside B1

Eleutheroside B1 

目录号: HY-135646 纯度: 98.73%
COA 产品使用指南

Eleutheroside B1,香豆素化合物,具有广谱的抗人流感病毒 (influenza virus) 作用,其IC50 值为 64-125μg/ml。Eleutheroside B1 通过 POLR2A 和 N-糖基化介导其抗流感活性。Eleutheroside B1 抑制多种趋化因子基因和流感病毒核蛋白 (NP) 基因的 mRNA 表达,且具有较低的细胞毒性。具有抗病毒、抗炎活性。

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Eleutheroside B1 Chemical Structure

Eleutheroside B1 Chemical Structure

CAS No. : 16845-16-2

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规格 价格 是否有货 数量
1 mg ¥2500
In-stock
5 mg ¥5500
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eleutheroside B1, a coumarin compound, has a wide spectrum of anti-human influenza virus efficacy, with an IC50 value of 64-125 µg/ml. Eleutheroside B1 mediates its anti-influenza activity through POLR2A and N-glycosylation. Eleutheroside B1 inhibits the mRNA expression of several chemokine genes and the influenza nucleoprotein (NP) gene, and exhibits low cytotoxicity. Antiviral and anti-inflammatory activities[1].

体外研究
(In Vitro)

Eeutheroside B1 (100 µg/ml; 24 hours) influences mRNA expression of host genes and virus genes in A549 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RT-PCR[1]

Cell Line: Virus-infected A549 cells
Concentration: 100 µg/ml
Incubation Time: 24 hours
Result: The expression of host genes (MAN2A2, POLR2A) and virus genes (PA, PB1, PB2, HA) were decreased.
分子量

384.33

Formula

C17H20O10

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料
参考文献

Eleutheroside B1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Eleutheroside B1
目录号:
HY-135646
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