2. Protein Tyrosine Kinase/RTK
  3. FAK
  4. FAK-IN-6

FAK-IN-6 是一种有效的 FAK 抑制剂，IC50 为 1.415 nM。FAK-IN-6 对某些癌症细胞系具有抗增殖活性。FAK-IN-6 可用于胰腺癌的研究。

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FAK-IN-6 Chemical Structure

FAK-IN-6 Chemical Structure

CAS No. : 3033299-38-3

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FAK-IN-6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FAK-IN-6 is a potent FAK inhibitor with an IC50 value of 1.415 nM. FAK-IN-6 has anti-proliferative activity against certain cancer cell lines. FAK-IN-6 can be used for researching pancreatic cancer[1].

IC50 & Target

IC50: 1.415 nM (FAK)[1]
体外研究
(In Vitro)

FAK-IN-6 (compound 9h) (0-10 μM; 72 h) has anti-proliferative activity against pancreatic cancer cells, lung cancer cells and lymphoma cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

FAK-IN-6 相关抗体:

Cell Proliferation Assay[1]

Cell Line: AsPC-1, PaCa-2, H1975, KM3/BTZ, Raji and L-02[1]
Concentration: 0-10 μM
Incubation Time: 72 h
Result: Exhibited anti-proliferative activity against AsPC-1, PaCa-2, H1975, KM3/BTZ, Raji and L-02 with IC50s of 0.9886 ± 0.0086 μM, 5.274 ± 0.9312 μM, 2.918 ± 0.0821 μM, 2.315 ± 0.2969 μM, 1.320 ± 0.2973 μM and 1.220 ± 0.2683 μM.
分子量

596.04

Formula

C25H31ClN5O6PS
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FAK-IN-6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FAK-IN-63033299-38-3FAKPTK2 protein tyrosine kinase 2PTK2Focal adhesion kinaseAnticancerpancreatic cancerlung cancerlymphomaInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-150730
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