1. Immunology/Inflammation
  2. Complement System
  3. FD-IN-1

FD-IN-1 

目录号: HY-128570
产品使用指南

FD-IN-1 (Compound 12) 是一种补体因子 D (FD) 抑制剂,IC50 为 12 nM。补体因子 D 是一种高特异性的 S1 丝氨酸蛋白酶,在先天免疫系统的替代补体途径中起着重要作用。FD-IN-1 还抑制因子 XIa (FXIa) 和类胰蛋白酶 β2,IC50 分别为 7.7 和 6.5 μM。

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FD-IN-1 Chemical Structure

FD-IN-1 Chemical Structure

CAS No. : 1646682-14-5

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Description

FD-IN-1 (Compound 12) is a factor D (FD) inhibitor with an IC50 of 12 nM. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system. FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5µM, respectively[1].

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

377.43

Formula

C₂₃H₂₃NO₄

CAS No.

1646682-14-5

SMILES

O=C(O)CC1=CC=CC=C1OCC2=CC=CC(C3=CC([C@H](N)CO)=CC=C3)=C2

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
FD-IN-1
目录号:
HY-128570
需求量:

FD-IN-1

Cat. No.: HY-128570