2. Peptides
  3. G7-18NATE

G7-18NATE 是 Grb7 的肽抑制剂。HY-P10224 以微摩尔亲和力 (KD = 18.1 μM) 结合 Grb7-SH2 结构域。G7-18NATE 可抑制多种癌细胞系的细胞增殖、运动、细胞侵袭和 3D 培养物形成。

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Custom Peptide Synthesis

G7-18NATE Chemical Structure

G7-18NATE Chemical Structure

CAS No. : 936728-13-1

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G7-18NATE 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

G7-18NATE is a peptide inhibitor of Grb7. HY-P10224 binds to the Grb7-SH2 domain with micromolar affinity (KD = 18.1 μM). G7-18NATE inhibits cell proliferation, motility, cell invasion and 3D culture formation in several cancer cell lines[1][2].

体外研究
(In Vitro)

G7-18NATE (10 μM, 24 h) 抑制 MDA-MB-468 细胞迁移[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

G7-18NATE 相关抗体:
分子量

1417.50

Formula

C67H80N14O19S
CAS 号
Sequence

cyclo(CH2CO-Trp-Phe-Glu-Gly-Tyr-Asp-Asn-Thr-Phe-Pro-Cys(NH2)-S-)
Sequence Shortening

cyclo(CH2CO-WFEGYDNTFP-Cys(NH2)-S-)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

G7-18NATE936728-13-1OthersanticancerpeptideInhibitorinhibitorinhibit

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产品名称：
G7-18NATE
目录号：
HY-P10224
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