2. Peptides
  3. GAD65 (524-543)

GAD65 (524-543) 是一种有生物活性的肽。(这是谷氨酸脱羧酶 65 (GAD65) 的氨基酸 524 至 543 片段。它是该胰岛抗原的首批片段之一，可在自发性自身免疫性糖尿病的非肥胖糖尿病 (NOD) 小鼠模型中诱导增殖性 T 细胞反应。该肽是对自发产生的糖尿病 T 细胞克隆 BDC2.5 的特异性刺激，可能亲和力较低。 p524-543 免疫增加了 NOD 小鼠对 BDC2.5 T 细胞过继转移诱导的 1 型糖尿病的易感性。)

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GAD65 (524-543) Chemical Structure

GAD65 (524-543) Chemical Structure

CAS No. : 152468-44-5

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GAD65 (524-543) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

GAD65 (524-543) is a biological active peptide. (This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.)

分子量

2238.67

Formula

C97H168N28O28S2
CAS 号
Sequence

Ser-Arg-Leu-Ser-Lys-Val-Ala-Pro-Val-Ile-Lys-Ala-Arg-Met-Met-Glu-Tyr-Gly-Thr-Thr
Sequence Shortening

SRLSKVAPVIKARMMEYGTT
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GAD65 (524-543)152468-44-5OthersInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P5396
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