Gnrhr - gonadotropin releasing hormone receptor Gene

中文名称：促性腺激素释放激素受体

种属: Mus musculus

关于 Gnrhr

功能概要

预测该基因编码的蛋白编码的蛋白可启动促性腺激素释放激素受体活性；生长激素释放激素受体活性；和肽结合活性。预计参与 G 蛋白偶联受体信号通路和细胞群增殖的负调控。预测作用于信号转导的上游或内部。预测位于质膜中。预计是质膜的组成部分。以多种结构表达，包括腺垂体；颚;下颌过程;和卵巢。用于研究伴有或不伴有嗅觉丧失的低促性腺激素性性腺功能减退症 7 。该基因的人类直系同源物与低促性腺激素性性腺功能减退症 7 相关，伴有或不伴有嗅觉缺失。与人类 GNRHR（促性腺激素释放激素受体）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable gonadotropin-releasing hormone receptor activity; growth hormone-releasing hormone receptor activity; and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and negative regulation of cell population proliferation. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including adenohypophysis; jaw; mandibular process; and ovary. Used to study hypogonadotropic hypogonadism 7 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia. Orthologous to human GNRHR (gonadotropin releasing hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]